The effect of three different solutions on preventing oral mucositis in cancer patients undergoing stem cell transplantation: A non-randomized controlled trial: A Turkish study

dc.contributor.authorHarman, Merve
dc.contributor.authorOvayolu, Nimet
dc.contributor.authorUçan Ovayolu, Özlem
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T19:35:26Z
dc.date.available10.07.201910:49:14
dc.date.available2019-07-10T19:35:26Z
dc.date.issued2019
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıkları Ana Bilim Dalı
dc.description.abstractOBJECTIVE: To evaluate the effect of different solutions administered to patients undergoing stem cell transplantation on oral mucositis. METHODS: The non-randomised controlled trial was conducted at a Istanbul Medipol Mega university hospital in Turkey between May 2014 and June 2016, and comprised patients undergoing stem cell transplantation. They were divided into three groups. Group 1 had patients using chlorhexidine gluconate and benzydamine hydrochloride solution. Group 2 had those using calcium and phosphate solution. Group 3 patients were using black mulberry syrup. Data was collected using a structured questionnaire and the World Health Organisation mucositis assessment scale. Assessment was done on days 7, 14 and 21. Clinical significance of oral solutions was statistically determined. RESULTS: Of the 83 patients, 30(36%) were in group 1, 28(34%) in group 2, and 25(30%) in group 3. On day 7, there was no significant difference in terms of grades among the groups (p>0.05). On day 14, grade 2 mucositis was seen in 2(8%) patents in group 3, 5(17.9%) in group 2 and 5(16.7%) in group 1; Grade 3 mucositis was seen in 2(6.7%) patients in group 1, but none in the other two groups. On day 21, grade 3 mucositis was present in 2(8.0%) in group 3, 2(7.1%) in group 2, and 4(13.3%) in group 1. CONCLUSIONS: The use of black mulberry and calcium-phosphate solutions was found to be beneficial in preventing and treating oral mucositis.
dc.identifier.citationHarman, M., Ovayolu, N. ve Uçan Ovayolu, Ö. (2019). The effect of three different solutions on preventing oral mucositis in cancer patients undergoing stem cell transplantation: A non-randomized controlled trial: A Turkish study. Journal of the Pakistan Medical Association, 69(6), 811-816. https://dx.doi.org/10.5812/ircmj.24775
dc.identifier.endpage816
dc.identifier.issn0030-9982
dc.identifier.issue6
dc.identifier.scopusqualityQ3
dc.identifier.startpage811
dc.identifier.urihttps://dx.doi.org/10.5812/ircmj.24775
dc.identifier.urihttps://hdl.handle.net/20.500.12511/776
dc.identifier.volume69
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherPakistan Medical Association
dc.relation.ispartofJournal of the Pakistan Medical Associationen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectStem Cell Transplantation
dc.subjectOral Mucositis
dc.subjectNursing
dc.titleThe effect of three different solutions on preventing oral mucositis in cancer patients undergoing stem cell transplantation: A non-randomized controlled trial: A Turkish study
dc.typeArticle

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