Comparison of fentanil and remifentanil for coronary artery surgery with low ejection fraction

dc.authorid0000-0001-9338-8152
dc.authorid0000-0001-6643-9364
dc.authorid0000-0001-5485-5440
dc.contributor.authorBaddal, Nükhet
dc.contributor.authorConkbayır, Cenk
dc.contributor.authorErdemli, Özcan
dc.contributor.authorKaradeniz, Ümit
dc.contributor.authorTezcan, Büşra
dc.contributor.authorÖztaş, Didem Melis
dc.contributor.authorBeyaz, Metin Onur
dc.contributor.authorUğurlucan, Murat
dc.contributor.authorYıldız, Yahya
dc.contributor.authorYavaş, Soner
dc.date.accessioned2021-04-05T07:09:29Z
dc.date.available2021-04-05T07:09:29Z
dc.date.issued2020
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Anesteziyoloji ve Reanimasyon Ana Bilim Dalı
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Kalp ve Damar Cerrahisi Ana Bilim Dalı
dc.description.abstractIntroduction: In this study, we evaluated patient response and haemodynamic parameters in patients with low ejection fraction undergoing coronary bypass surgery with either fentanil or remifentanil in conjunction with etomidate.Material and methods: We evaluated 30 cases of coronary artery surgery, which were divided into two treatment groups (n = 15 each). In group F (fentanil group), the following regimen was employed for anaesthesia induction: 1 mg/kg lidocaine, 0.3 mg/kg etomidate, and, following a 1 µg/kg 60 s bolus dose of fentanil, a 0.1 µg/kg/min fentanil infusion was initiated, after which 0.6 mg/kg rocuronium was administered. In group R (remifentanil group), the following regimen was employed for anaesthesia induction: 1 mg/kg lidocaine, 0.3 mg/kg etomidate and, following a 1 µg/kg 60 s bolus dose of remifentanil, a 0.1 µg/kg/min remifentanil infusion was initiated, after which 0.6 mg/kg rocuronium was administered. Systolic artery pressure, diastolic artery pressure, mean arterial pressure, heart rate, SPO2 (saturation), cardiac output, stroke volume variance, central venous pressure, and systemic vascular resistance values were recorded for all study patients at five minutes before anaesthetic induction (T1), immediately following induction (T2), and immediately following intubation (T3).Results: The demographic values obtained for both groups were similar. We found that remifentanil use was associated with decreased cardiac output and increased fluctuations in both heart rate and mean values of arterial pressure.Conclusions: Although many studies have demonstrated remifentanil to be as safe as fentanil when titrated to an appropriate dose, our study suggests that fentanil may be a more appropriate choice during the induction of anaesthesia in patients with a low ejection fraction.
dc.identifier.citationBaddal, N., Conkbayır, C., Erdemli, Ö., Karadeniz, Ü., Tezcan, B., Öztaş, D. M. ... Yavaş, S. (2020). Comparison of fentanil and remifentanil for coronary artery surgery with low ejection fraction. Archives of Medical Science - Atherosclerotic Diseases, 5, e20-e26. https://doi.org/10.5114/amsad.2020.93528
dc.identifier.doi10.5114/amsad.2020.93528
dc.identifier.endpagee26
dc.identifier.issn2451-0629
dc.identifier.startpagee20
dc.identifier.urihttps://doi.org/10.5114/amsad.2020.93528
dc.identifier.urihttps://hdl.handle.net/20.500.12511/6685
dc.identifier.volume5
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherTermedia Publishing House Ltd.
dc.relation.ispartofArchives of Medical Science - Atherosclerotic Diseasesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectAnaesthesia
dc.subjectCoronary Artery Bypass Surgery
dc.subjectLow Ejection Fraction
dc.titleComparison of fentanil and remifentanil for coronary artery surgery with low ejection fraction
dc.typeArticle

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