Portocaval shunts' role in gut microbiota and hepatic encephalopathy: the gut-to-brain pathway

Yakut, Aysun

Portocaval shunts' role in gut microbiota and hepatic encephalopathy: the gut-to-brain pathway

dc.contributor.author	Yakut, Aysun
dc.date.accessioned	2025-11-05T13:16:16Z
dc.date.available	2025-11-05T13:16:16Z
dc.date.issued	2024
dc.department	İstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıkları Ana Bilim Dalı
dc.description.abstract	I read the study by Zhao et al with great interest. Although the study design was quite complicated, it was successful in raising awareness of science and relevant researchers. Thirty patients with liver cirrhosis and portal hypertension secondary to chronic hepatitis B were included in the study. They were treated for variceal bleeding and underwent trans-jugular intrahepatic portosystemic shunt to prevent the recurrence of variceal bleeding and to reduce portal pressure. The authors evaluated the effects of changes in gut microbiota (GM) on hepatic encephalopathy secondary to portocaval bypass. The GM is greatly affected by local and general factors, including herbal and medical drugs, a person's dietary characteristics (carnivorous, vegan, vegetarian), supplementary foods, drinking water sources, and living in a city center or town. Therefore, I congratulate Zhao et al for their concise and comprehensive study on a multifactorial subject.
dc.identifier.citation	Yakut, A. (2024). Portocaval shunts' role in gut microbiota and hepatic encephalopathy: the gut-to-brain pathway. World Journal of Gastroenterology, 30(43), 4672-4676. http://dx.doi.org/10.3748/wjg.v30.i43.4672
dc.identifier.doi	10.3748/wjg.v30.i43.4672
dc.identifier.endpage	4676
dc.identifier.issn	1007-9327
dc.identifier.issn	2219-2840
dc.identifier.issue	43
dc.identifier.pmid	39575404
dc.identifier.scopus	2-s2.0-85208244454
dc.identifier.scopusquality	Q1
dc.identifier.startpage	4672
dc.identifier.uri	http://dx.doi.org/10.3748/wjg.v30.i43.4672
dc.identifier.uri	https://hdl.handle.net/20.500.12511/13162
dc.identifier.volume	30
dc.identifier.wos	WOS:001360211000008
dc.identifier.wosquality	Q1
dc.indekslendigikaynak	Web of Science
dc.indekslendigikaynak	Scopus
dc.indekslendigikaynak	PubMed
dc.institutionauthor	Yakut, Aysun
dc.institutionauthorid	0000-0001-7792-8438
dc.language.iso	en
dc.relation.ispartof	World Journal of Gastroenterology
dc.relation.publicationcategory	Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rights	info:eu-repo/semantics/openAccess
dc.rights	Attribution-NonCommercial 4.0 International
dc.rights.uri	https://creativecommons.org/licenses/by-nc/4.0/
dc.subject	Chronic Hepatitis B
dc.subject	Hepatic Encephalopathy
dc.subject	Intestinal Microbiota
dc.subject	Liver Cirrhosis
dc.subject	Transjugular Intrahepatic Portosystemic Shunt
dc.title	Portocaval shunts' role in gut microbiota and hepatic encephalopathy: the gut-to-brain pathway
dc.type	Article