Cerebral proliferative angiopathy accompanied by cerebral cavernous malformation: A case report

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dc.authorid0000-0001-7396-0449
dc.authorid0000-0002-0742-1305
dc.authorid0000-0003-0020-3759
dc.contributor.authorEngin, Eyüp Furkan
dc.contributor.authorPolat, Burcu
dc.contributor.authorErtan Akan, Gülhan
dc.contributor.authorAkgül, Erol
dc.date.accessioned2021-11-29T11:24:01Z
dc.date.available2021-11-29T11:24:01Z
dc.date.issued2021
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Nöroloji Ana Bilim Dalı
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Radyoloji Ana Bilim Dalı
dc.departmentİstanbul Medipol Üniversitesi, Uluslararası Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Radyoloji Ana Bilim Dalı
dc.description.abstractCerebral Proliferative Angiopathy (CPA) is a rare vascular malformation that is distinguished from classical brain arteriovenous malformations (AVM) in its imaging findings and clinical progression but more importantly in its pathophysiology. Here we report the case of a 37-year-old male patient with CPA accompanied by Cerebral Cavernous Malformation (CCM) in hopes to expand the inquiry into the pathophysiology of this rare lesion. A patient with progressive headache, right-sided weakness, and impaired speech were evaluated at our medical center. Neuroimaging studies were performed, and the patient was diagnosed with CPA. The patient has been followed up with conservative management and periodic neuroradiological evaluation for 5 years. Digital subtraction angiography (DSA) showed a vascular malformation diffusely covering the left hemisphere that is consistent with CPA. In addition, 2 sequential CCMs were detected in the right hemisphere. Also, the patients’ familial history included two brothers with CCMs. The coexistence of CPA with CCM and patients’ familial history of CCM could suggest the possibility of a common pathophysiological element.
dc.identifier.citationEngin, E. F., Polat, B., Ertan Akan, G. ve Akgül, E. (2021). Cerebral proliferative angiopathy accompanied by cerebral cavernous malformation: A case report. Clinical Neurology and Neurosurgery, 210. https://dx.doi.org/10.1016/j.clineuro.2021.107011
dc.identifier.doi10.1016/j.clineuro.2021.107011
dc.identifier.issn0303-8467
dc.identifier.scopusqualityQ2
dc.identifier.urihttps://dx.doi.org/10.1016/j.clineuro.2021.107011
dc.identifier.urihttps://hdl.handle.net/20.500.12511/8587
dc.identifier.volume210
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherElsevier B. V.
dc.relation.ispartofClinical Neurology and Neurosurgeryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/embargoedAccess
dc.subjectCerebral Cavernous Malformation
dc.subjectAngiopathy
dc.subjectCerebral Proliferative
dc.titleCerebral proliferative angiopathy accompanied by cerebral cavernous malformation: A case report
dc.typeArticle

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