New hematological parameters as early diagnosis and prognostic markers in critically patients

dc.authorid0000-0003-2641-3965
dc.contributor.authorGüllüpınar, Birdal
dc.contributor.authorSağlam, Caner
dc.contributor.authorYavru, Emine Vildan
dc.contributor.authorAksoy, Elif Eren
dc.contributor.authorKoran, Serhat
dc.contributor.authorEvrin, Togay
dc.contributor.authorÜnlüer, Erden Erol
dc.date.accessioned2022-07-18T12:10:31Z
dc.date.available2022-07-18T12:10:31Z
dc.date.issued2022
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Aile Hekimliği Ana Bilim Dalı
dc.description.abstractINTRODUCTION: Nucleated red blood cells and immature granulocytes are not normally detected in the blood of healthy adults. We aimed to investigate the effect of nucleated red blood cells and immature granulocytes on mortality in order to identify critically ill patients who were admitted to the emergency department, at high risk of death, and who was not traumatic. MATERIAL AND METHODS: This study was performed retrospectively in the emergency department of a tertiary education and research hospital between January 2021 and June 2021. All patients who died out of trauma and patients who were discharged from the emergency department on the same day were included. Nucleated red blood cells and immature granulocytes parameters were compared between the two groups. The primary outcome was all-cause death in the emergency department. RESULTS: Of the 188 patients included in the study, 129 (68.6%) were male. Nucleated red blood cells (1.88 ± 6.9/?L; 0.02 ± 0.08), % immature granulocytes (2.91 ± 3.04/?L; 0.58 ± 1.63) and immature red blood cells in deceased patients' granulocyte count (0.38 ± 0.46/?L; 0.04 ± 0.04) was significantly more significant than the control group (p < 0.001). When the area under the curve was examined, the highest value was found in nucleated red blood cells (Area under the curve = 0.920, p < 0.001). In multivariate regression analysis, high nucleated red blood cells, immature granulocyte count, and white blood cell levels were associated with all-cause mortality in the emergency department. CONCLUSIONS: High nucleated red blood cells and immature granulocyte levels may be associated with increased mortality during admission to the emergency department.
dc.identifier.citationGüllüpınar, B., Sağlam, C., Yavru, E. V., Aksoy, E. E., Koran, S., Evrin, T. ... Ünlüer, E. E. (2022). New hematological parameters as early diagnosis and prognostic markers in critically patients. Disaster and Emergency Medicine Journal, 7(2), 100-106. https://doi.org/10.5603/DEMJ.a2022.0020
dc.identifier.doi10.5603/DEMJ.a2022.0020
dc.identifier.endpage106
dc.identifier.issn2451-4691
dc.identifier.issue2
dc.identifier.scopus2-s2.0-85133554715
dc.identifier.scopusqualityQ3
dc.identifier.startpage100
dc.identifier.urihttps://doi.org/10.5603/DEMJ.a2022.0020
dc.identifier.urihttps://hdl.handle.net/20.500.12511/9578
dc.identifier.volume7
dc.indekslendigikaynakScopus
dc.institutionauthorKoran, Serhat
dc.language.isoen
dc.publisherVia Medica
dc.relation.ispartofDisaster and Emergency Medicine Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International*
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectCritically Patients
dc.subjectDeath
dc.subjectEmergency Department
dc.subjectImmature Granulocyte
dc.subjectNucleated Red Blood Cells
dc.titleNew hematological parameters as early diagnosis and prognostic markers in critically patients
dc.typeArticle

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