Relationship between fragmented qrs complex and early left ventricular dysfunction after mitral valve repair

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dc.authorid0000-0003-1919-3183
dc.authorid0000-0003-0230-6575
dc.authorid0000-0003-1320-9033
dc.authorid0000-0001-5825-8627
dc.authorid0000-0002-4607-5724
dc.authorid0000-0001-5074-5340
dc.authorid0009-0005-2888-3524
dc.authorid0000-0002-6161-3594
dc.contributor.authorKızılırmak Yılmaz, Filiz
dc.contributor.authorÇakal, Beytullah
dc.contributor.authorYılmaz, Fatih
dc.contributor.authorYazar, Arzu
dc.contributor.authorSavur, Ümeyir
dc.contributor.authorAkhundova, Aysel
dc.contributor.authorGüneş, Hacı Murat
dc.contributor.authorGüler, Ekrem
dc.contributor.authorDursun, Atakan
dc.contributor.authorYousufzai, Navin
dc.contributor.authorGüden, Mustafa
dc.date.accessioned2024-05-02T12:59:25Z
dc.date.available2024-05-02T12:59:25Z
dc.date.issued2024
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Kardiyoloji Ana Bilim Dalı
dc.description.abstractBackground: Preoperative left ventricular (LV) ejection fraction (PreLVEF) and preoperative LV end-systolic diameter (PreESD) are known predictors for postoperative LV dysfunction after mitral valve repair (MVR). Fragmented QRS (fQRS) evaluated in 12-derivation electrocardiography has widely been accepted as a sign of myocardial fibrosis. In the present study, we aimed to evaluate the relationship between fQRS in preoperative 12?lead electrocardiography (ECG) and postoperative LV dysfunction that develop after MVR in patients with severe primary mitral regurgitation (MR) due to mitral valve prolapse (MVP). Methods: From 2019 to 2022, 49 patients who had undergone successful MVR surgery for severeMR caused by MVP were enrolled in the study. The preoperative and postoperative echocardiographic data were collected retrospectively. We analyzed the demographic, echocardiographic, operative and postoperative parameters to assess the relationship between fQRS and early postoperative LV dysfunction, defined as an LVEF<60%. Results: PreLVEF of all patients were ? %65. A total of 22 patients had fQRS (44.9%) and postoperative LV dysfunction was found to be 36.7%. A significantly higher rate of fQRS was observed in the group with postoperative LV dysfunction compared to the group without (12 (66.7%) vs 10 (32.3%), p: 0.036). In multivariate analysis for fQRS, PreESD, preoperative pulmonary artery systolic pressure (PrePASP), preoperative atrial fibrillation (PreAF), and male gender, only fQRS was found to be a significant predictor of postoperative LV dysfunction (p: 0.003, OR: 4.28, 95% CI (1.15–15.96). Conclusion: fQRS was found to be a predictor of postoperative LV dysfunction in the early period after MVR. fQRS may be a readily available and cost-effective test that can be used in clinical practice to predict postoperative LV dysfunction in patients undergoing MVR.
dc.identifier.citationKızılırmak Yılmaz, F., Çakal, B., Yılmaz, F., Yazar, A., Savur, Ü., Akhundova, A. ve Güden, M. (2024). Relationship between fragmented qrs complex and early left ventricular dysfunction after mitral valve repair. Journal of Electrocardiology, 84, 65-69. http://dx.doi.org/10.1016/j.jelectrocard.2024.03.001
dc.identifier.doi10.1016/j.jelectrocard.2024.03.001
dc.identifier.endpage69
dc.identifier.issn0022-0736
dc.identifier.pmid38537455
dc.identifier.scopus2-s2.0-85188846038
dc.identifier.scopusqualityQ3
dc.identifier.startpage65
dc.identifier.urihttp://dx.doi.org/10.1016/j.jelectrocard.2024.03.001
dc.identifier.urihttps://hdl.handle.net/20.500.12511/12428
dc.identifier.volume84
dc.identifier.wos001222842400001en_US
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorKızılırmak Yılmaz, Filiz
dc.institutionauthorÇakal, Beytullah
dc.institutionauthorYazar, Arzu
dc.institutionauthorSavur, Ümeyir
dc.institutionauthorAkhundova, Aysel
dc.institutionauthorGüneş, Hacı Murat
dc.institutionauthorGüler, Ekrem
dc.institutionauthorDursun, Atakan
dc.institutionauthorYousufzai, Navin
dc.institutionauthorGüden, Mustafa
dc.language.isoen
dc.relation.ispartofJournal of Electrocardiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectFragmented QRS
dc.subjectLeft Ventricular Dysfunction
dc.subjectMitral Valve Prolapse
dc.subjectMitral Valve Repair
dc.titleRelationship between fragmented qrs complex and early left ventricular dysfunction after mitral valve repair
dc.typeArticle

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