Contemporary patterns of presentation, diagnostics and management of upper tract urothelial cancer in 101 centres: The Clinical Research Office of the Endourological Society Global upper tract urothelial carcinoma registry
| dc.authorid | 0000-0002-6308-1763 | |
| dc.authorid | 0000-0003-0906-4417 | |
| dc.contributor.author | Baard, Joyce | |
| dc.contributor.author | Cormio, Luigi | |
| dc.contributor.author | Cavadas, Vítor | |
| dc.contributor.author | Alcaraz, Antonio | |
| dc.contributor.author | Shariat, Shahrokh F. | |
| dc.contributor.author | de la Rosette, Jean J. M. C. H. | |
| dc.contributor.author | Laguna, María Pilar | |
| dc.date.accessioned | 2021-06-11T06:45:45Z | |
| dc.date.available | 2021-06-11T06:45:45Z | |
| dc.date.issued | 2021 | |
| dc.department | İstanbul Medipol Üniversitesi, Uluslararası Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Üroloji Ana Bilim Dalı | |
| dc.description.abstract | PURPOSE OF REVIEW: To assess patterns of presentation, diagnostics and treatment in patients with upper tract urothelial carcinoma (UTUC), a multicentre registry was launched. Clinical data of UTUC patients were prospectively collected over a 5-year period. RECENT FINDINGS: Data from 2380 patients were included from 2014 to 2019 (101 centres in 29 countries). Patients were predominantly male (70.5%) and 53.3% were past or present smokers. The majority of patients (58.1%) were evaluated because of symptoms, mainly macroscopic hematuria. Computed tomography (CT) was the most common performed imaging modality (90.5%). A ureteroscopy (URS) was part of the diagnostic process in 1184 (49.7%) patients and 488 (20.5%) patients were treated endoscopically. In total, 1430 patients (60.1%) were treated by a radical nephroureterectomy, 59% without a prior diagnostic URS. Eighty-two patients (3.4%) underwent a segmental resection, 19 patients (0.8%) were treated by a percutaneous tumour resection. SUMMARY: Our data is in line with the known epidemiologic characteristics of UTUC. CT imaging is the preferred imaging modality as also recommended by guidelines. Diagnostic URS gained a stronger position, however, in almost half of patients a definitive treatment decision was made without complete endoscopic information. Only one-third of patients with UTUC are currently treated with kidney sparing surgery. | |
| dc.identifier.citation | Baard, J., Cormio, L., Cavadas, V., Alcaraz, A., Shariat, S. F., de la Rosette, J. J. M. C. H. ... Laguna, M. P. (2021). Contemporary patterns of presentation, diagnostics and management of upper tract urothelial cancer in 101 centres: The Clinical Research Office of the Endourological Society Global upper tract urothelial carcinoma registry. Current Opinion in Urology, 31(4), 354-362. https://dx.doi.org/10.1097/MOU.0000000000000899 | |
| dc.identifier.doi | 10.1097/MOU.0000000000000899 | |
| dc.identifier.endpage | 362 | |
| dc.identifier.issn | 1473-6586 | |
| dc.identifier.issn | 0963-0643 | |
| dc.identifier.issue | 4 | |
| dc.identifier.scopusquality | Q2 | |
| dc.identifier.startpage | 354 | |
| dc.identifier.uri | https://dx.doi.org/10.1097/MOU.0000000000000899 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12511/7130 | |
| dc.identifier.volume | 31 | |
| dc.identifier.wosquality | Q3 | |
| dc.indekslendigikaynak | Web of Science | |
| dc.indekslendigikaynak | Scopus | |
| dc.indekslendigikaynak | PubMed | |
| dc.language.iso | en | |
| dc.publisher | NLM (Medline) | |
| dc.relation.ispartof | Current Opinion in Urology | en_US |
| dc.relation.publicationcategory | Diğer | |
| dc.rights | info:eu-repo/semantics/embargoedAccess | |
| dc.subject | Diagnostics | |
| dc.subject | Management | |
| dc.subject | Urothelial Cancer | |
| dc.subject | Upper Tract Urothelial Carcinoma | |
| dc.title | Contemporary patterns of presentation, diagnostics and management of upper tract urothelial cancer in 101 centres: The Clinical Research Office of the Endourological Society Global upper tract urothelial carcinoma registry | |
| dc.type | Review Article |
