Breast artery calcification as an opportunistic predictor of cardiovascular disease

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dc.contributor.authorOkşul, Metin
dc.contributor.authorŞener, Yusuf Ziya
dc.contributor.authorSarıkaya, Yasin
dc.contributor.authorSarıkaya, Sevtap
dc.contributor.authorYıldırım, Arzu
dc.contributor.authorCanpolat, Uğur
dc.contributor.authorAkpınar, Meltem Gülsün
dc.contributor.authorHazırolan, Tuncay
dc.contributor.authorÖzer, Necla
dc.contributor.authorTokgözoğlu, Sadberk Lale
dc.date.accessioned2023-09-20T08:46:22Z
dc.date.available2023-09-20T08:46:22Z
dc.date.issued2023
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Kardiyoloji Ana Bilim Dalı
dc.description.abstractBackground Atherosclerotic cardiovascular disease is still the leading cause of mortality for women. Breast cancer screening with mammography is recommended in all women aged over 40 years. Aims Whether breast artery calcification (BAC) is associated with cardiovascular disease is not clear. We aimed to evaluate the association between BAC and the presence of coronary atherosclerosis determined by CT. Methods All patients who underwent both mammography and coronary CT angiography between January 2010 and December 2016 were screened, and patients with a duration of less than 12 months between CT and mammography were included. Results A total of 320 women were included and BAC was detected in 47 (14.6%) patients. BAC was correlated with age and CT coronary calcium score. Both the frequency of critical coronary artery stenosis (34% vs 10.6%; p = 0.001) and CT coronary calcium score (5.5 vs 0; p = 0.001) was significantly higher in patients with BAC. The absence of BAC was a strong predictor of the absence of significant coronary artery disease (p = 0.001). BAC was independently associated with all-cause mortality after excluding patients with breast cancer (HR: 5.32; p = 0.013). Conclusion Breast artery calcification is associated with coronary calcium score and significant coronary stenosis. A high BAC score is related to increased mortality.
dc.identifier.citationOkşul, M., Şener, Y. Z., Sarıkaya, Y., Sarıkaya, S., Yıldırım, A., Canpolat, U. ... Tokgözoğlu, S. L. (2023). Breast artery calcification as an opportunistic predictor of cardiovascular disease. Irish Journal of Medical Science, 192(2), 625-631. https://doi.org/10.1007/s11845-022-03127-2
dc.identifier.doi10.1007/s11845-022-03127-2
dc.identifier.endpage631
dc.identifier.issn0021-1265
dc.identifier.issn1863-4362
dc.identifier.issue2
dc.identifier.pmid35971037
dc.identifier.scopus2-s2.0-85136084551
dc.identifier.scopusqualityQ3
dc.identifier.startpage625
dc.identifier.urihttps://doi.org/10.1007/s11845-022-03127-2
dc.identifier.urihttps://hdl.handle.net/20.500.12511/11468
dc.identifier.volume192
dc.identifier.wos000840606900002en_US
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorYıldırım, Arzu
dc.language.isoen
dc.publisherSpringer
dc.relation.ispartofIrish Journal of Medical Scienceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectBreast Artery Calcification
dc.subjectCardiovascular Risk
dc.subjectCoronary Calcium Score
dc.titleBreast artery calcification as an opportunistic predictor of cardiovascular disease
dc.typeArticle

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