The cancer of the bladder risk assessment score and mortality-survival relationship among patients who have undergone radical cystectomy in the Turkish urooncology association database
| dc.authorid | 0000-0003-0956-7460 | |
| dc.contributor.author | Tavukçu, Hasan Hüseyin | |
| dc.contributor.author | Tinay, İlker | |
| dc.contributor.author | İzol, Volkan | |
| dc.contributor.author | Baltacı, Sümer | |
| dc.contributor.author | Teke, Kerem | |
| dc.contributor.author | Süer, Evren | |
| dc.contributor.author | Yücetaş, Uğur | |
| dc.contributor.author | Yazıcı, Sertaç | |
| dc.contributor.author | Akan, Serkan | |
| dc.date.accessioned | 2025-02-19T06:52:53Z | |
| dc.date.available | 2025-02-19T06:52:53Z | |
| dc.date.issued | 2024 | |
| dc.department | İstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Üroloji Ana Bilim Dalı | |
| dc.description.abstract | Objective: The Cancer of the Bladder Risk Assessment (COBRA) score is a practical method that can be used to predict survival in patients who have undergone radical cystectomy (RC). We aimed to evaluate COBRA scores in our patient group. Materials and Methods: Patients were classified according to tumor stage and lymph node (TLN) involvement; mortality rates and survival were analyzed according to both the TLN classification and COBRA score from the Turkish Urooncology Association database. The chi-square test and Fisher-Freeman-Halton Exact chi-square test were used to compare qualitative data as well as descriptive statistical methods. Cox regression analysis was used for multivariate analysis. Kaplan- Meier and log-rank tests were used for survival analysis. Results: There was a statistically significant difference between the COBRA scores and survival rates in terms of cancer-specific mortality according to TLN classification (p=0.000; p<0.05). A COBRA score of 6 was associated with a lower mortality rate than a COBRA score of 5. In the Cox regression analysis of cancer-related death, a one-unit increase in the COBRA score increased the cancer-related death rate 1.54-fold [hazard ratio (HR)=1.540; 95% confidence interval (CI)=1.402-1.691] (p<0.05). When the COBRA score was compared to 0, the highest risk was observed for COBRA 5. If the COBRA score was 5, the risk of cancer- related death increased 14.63 times (HR=14.627; 95% CI=7.041-30.385) (p<0.05). If the COBRA score was 6, the risk of cancer-related death increased by 11.54 times (HR=11.547; 95% CI=5.270-25.278) (p<0.05). Conclusion: The COBRA score increased, the prognosis worsened, and our results are consistent with the first validated study. | |
| dc.identifier.citation | Tavukçu, H. H., Tinay, İ., İzol, V., Baltacı, S., Teke, K., Süer, E. ... Şahin, B. (2024). The cancer of the bladder risk assessment score and mortality-survival relationship among patients who have undergone radical cystectomy in the Turkish urooncology association database. Bulletin of Urooncology, 23(2), 56-62. http://dx.doi.org/10.4274/uob.galenos.2024.2024.3.2 | |
| dc.identifier.doi | 10.4274/uob.galenos.2024.2024.3.2 | |
| dc.identifier.endpage | 62 | |
| dc.identifier.issn | 2147-2270 | |
| dc.identifier.issue | 2 | |
| dc.identifier.startpage | 56 | |
| dc.identifier.uri | http://dx.doi.org/10.4274/uob.galenos.2024.2024.3.2 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12511/12888 | |
| dc.identifier.volume | 23 | |
| dc.identifier.wos | WOS:001292819300003 | |
| dc.identifier.wosquality | Q4 | |
| dc.indekslendigikaynak | Web of Science | |
| dc.institutionauthor | Tavukçu, Hasan Hüseyin | |
| dc.institutionauthorid | 0000-0003-0956-7460 | |
| dc.language.iso | en | |
| dc.relation.ispartof | Bulletin of Urooncology | |
| dc.relation.publicationcategory | Makale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı | |
| dc.rights | info:eu-repo/semantics/openAccess | |
| dc.subject | Bladder Cancer | |
| dc.subject | Cystectomy | |
| dc.subject | Prognosis | |
| dc.title | The cancer of the bladder risk assessment score and mortality-survival relationship among patients who have undergone radical cystectomy in the Turkish urooncology association database | |
| dc.type | Article |
