Quantitative evaluation of the enamel caries which were treated with casein phosphopeptide-amorphous calcium fluoride phosphate

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dc.contributor.authorYazıcıoğlu, Oktay
dc.contributor.authorYaman, Batu Can
dc.contributor.authorGüler, Ali Umut
dc.contributor.authorKoray, Fatma
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T20:02:04Z
dc.date.available10.07.201910:49:13
dc.date.available2019-07-10T20:02:04Z
dc.date.issued2017
dc.departmentİstanbul Medipol Üniversitesi, Diş Hekimliği Fakültesi, Periodontoloji Ana Bilim Dalı
dc.descriptionWOS: 000407813400007
dc.descriptionPubMed ID: 28656922
dc.description.abstractObjectives: The aim of this in vivo study was to quantitatively evaluate the remineralization of the enamel caries on smooth and occlusal surfaces using DIAGNOdent, after daily application of casein phosphopeptide-amorphous calcium fluoride phosphate (CPP-ACFP). Materials and Methods: Thirty volunteers, aged 18u30 years, with white spot lesions on the smooth and occlusal surfaces of the teeth were included in the study. These white spot lesions were visually examined and the degree of demineralization was quantitatively evaluated using DIAGNOdent. Volunteers with lesions scored as enamel caries on smooth surfaces (n = 109) and on occlusal surfaces (n = 176) were randomly divided into control and study groups. Both groups were instructed regarding oral hygiene and were asked to brush their teeth with the same tooth paste and tooth brush. In the study group, CPP-ACFP was applied daily for 4 min on the existing enamel caries lesions. After 4 weeks, the mineralization changes in enamel caries on the smooth and occlusal surfaces were assessed by DIAGNOdent. Recorded data were statistically analyzed by Wilcoxon signed-rank test and MannuWhitney U-test. Results: Comparison of DIAGNOdent values evaluated before and after the application of CPP-ACFP showed that the remineralization of enamel caries lesions on smooth and occlusal surfaces occurred in the study group (both, P < 0.001). The control group showed no quantitative changes at the end of 4 weeks (P > 0.05). At the end of the study period, the DIAGNOdent values differed significantly between the control and study groups (P < 0.001). Conclusions: Daily local application of CPP-ACFP for 4 min for 4 weeks results in significant remineralization of the initial caries lesions. Clinical Relevance: CPP-ACFP can be used in the treatment of white spot lesions.
dc.identifier.citationYazıcıoğlu, O., Yaman, B. C., Güler, A. U. ve Koray, F. (2017). Quantitative evaluation of the enamel caries which were treated with casein phosphopeptide-amorphous calcium fluoride phosphate. Nigerian Journal of Clinical Practice, 20(6), 686-692. https://dx.doi.org/10.4103/1119-3077.180073
dc.identifier.doi10.4103/1119-3077.180073
dc.identifier.endpage692
dc.identifier.issn1119-3077
dc.identifier.issue6
dc.identifier.scopusqualityQ3
dc.identifier.startpage686
dc.identifier.urihttps://dx.doi.org/10.4103/1119-3077.180073
dc.identifier.urihttps://hdl.handle.net/20.500.12511/3539
dc.identifier.volume20
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherMedknow Publications & Media Pvt Ltd
dc.relation.ispartofNigerian Journal of Clinical Practiceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsAttribution-NonCommercial-ShareAlike 3.0 Unported*
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttps://creativecommons.org/licenses/by-nc-sa/3.0/*
dc.subjectCasein Phosphopeptide-Amorphous Calcium Phosphate
dc.subjectFluoride
dc.subjectNoncavitated Caries Lesions
dc.subjectRemineralization
dc.titleQuantitative evaluation of the enamel caries which were treated with casein phosphopeptide-amorphous calcium fluoride phosphate
dc.typeArticle

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