Regional variations in psoriatic arthritis: Insights from a nationwide multicenter analysis in Türkiye

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dc.contributor.authorKılıç, Erkan
dc.contributor.authorKılıç, Gamze
dc.contributor.authorTekeoğlu, İbrahim
dc.contributor.authorSargın, Betül
dc.contributor.authorTolu, Sena
dc.contributor.authorNas, Kemal
dc.date.accessioned2025-06-02T08:51:17Z
dc.date.available2025-06-02T08:51:17Z
dc.date.issued2024
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Fizik Tedavi ve Rehabilitasyon Ana Bilim Dalı
dc.description.abstractObjectives: The study aimed to investigate and compare clinical features, disease activity, and the overall disease burden among psoriatic arthritis (PsA) patients across seven distinct geographic regions in Türkiye. Patients and methods: A multicenter cross-sectional study involving 1,134 PsA patients from 25 referral centers across seven regions was conducted. Demographic and clinical characteristics, comorbidities, joint involvement, extra-articular manifestations, and disease activity measures were evaluated across regions. Results: A total of 1134 PsA patients from seven different geographic regions in Türkiye participated in this study. The highest number of participants was from the Marmara region (n=409), with subsequent representation from Central Anatolia (n=370), Aegean (n=139), Mediterranean (n=60), Black Sea (n=60), Eastern Anatolia (n=60), and Southeastern Anatolia (n=36) regions. There were significant variations in demographic profile, including age, body mass index, age of disease onset, educational status, comorbidities, and family history of both psoriasis and PsA. Clinical features, such as enthesitis, dactylitis, uveitis, and joint involvement, demonstrated significant variation across regions. Additionally, disease activity measures, including pain, patient and physician global assessments, acute phase reactants, disease activity indices, quality of life, and functional status, displayed considerable regional differences. Conclusion: This nationwide study revealed substantial regional diversity in demographic data, clinical characteristics, disease activity, and quality of life among PsA patients in Türkiye. These findings stress the need to customize treatment approaches to address regional needs and to conduct further research to uncover reasons for disparities. It is crucial to enhance region-specific approaches to improve patient care and outcomes for PsA.
dc.identifier.citationKılıç, E., Kılıç, G., Tekeoğlu, İ., Sargın, B., Tolu, S. ... Nas, K. (2024). Regional variations in psoriatic arthritis: Insights from a nationwide multicenter analysis in Türkiye. Archives of Rheumatology, 39(3), 339-349. http://dx.doi.org/10.46497/ArchRheumatol.2024.10591
dc.identifier.doi10.46497/ArchRheumatol.2024.10591
dc.identifier.endpage349
dc.identifier.issn2618-6500
dc.identifier.issue3
dc.identifier.pmid39507837
dc.identifier.scopus2-s2.0-85203023813
dc.identifier.scopusqualityQ3
dc.identifier.startpage339
dc.identifier.urihttp://dx.doi.org/10.46497/ArchRheumatol.2024.10591
dc.identifier.urihttps://hdl.handle.net/20.500.12511/12926
dc.identifier.volume39
dc.identifier.wosWOS:001306482800001
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorTolu, Sena
dc.institutionauthorid0000-0002-1111-3110
dc.language.isoen
dc.relation.ispartofArchives of Rheumatology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rightsAttribution-NonCommercial 4.0 International
dc.rights.urihttp://creativecommons.org/licen ses/by -nc/4 .0/
dc.subjectArthritis
dc.subjectDifferences
dc.subjectGeographic Locations
dc.subjectPsoriatic
dc.subjectRegional
dc.subjectSpondyloarthritis
dc.titleRegional variations in psoriatic arthritis: Insights from a nationwide multicenter analysis in Türkiye
dc.typeArticle

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