Ultrasound-guided bilateral erector spinae plane block in the management of postoperative analgesia in living liver donors: a randomized, prospective study

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dc.contributor.authorUludağ Yanaral, Tümay
dc.contributor.authorGüngör, Hande
dc.contributor.authorİnce, Ayşe
dc.contributor.authorÇelik, Erkan Cem
dc.contributor.authorYaprak, Onur
dc.contributor.authorAtalay, Yunus Oktay
dc.contributor.authorÇiftçi, Bahadır
dc.contributor.authorKaraaslan, Pelin
dc.date.accessioned2025-11-26T10:44:19Z
dc.date.available2025-11-26T10:44:19Z
dc.date.issued2024
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Anesteziyoloji ve Reanimasyon Ana Bilim Dalı
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Genel Cerrahi Ana Bilim Dalı
dc.description.abstractBACKGROUND: Living donor hepatectomy is a procedure associated with notable postoperative pain, impacting patient recovery and satisfaction. Addressing this challenge, we aimed to examine the effect of ultrasound-guided bilateral erector spinae plane block (ESPB) in postoperative analgesia management of patients undergoing living donor hepatectomy for liver transplantation. METHODS: Asingle-center prospective, randomized, controlled study was conducted on ASAI-IIpatients aged 18-65 who underwent elective living donor hepatectomy. Participants were randomized into ESPB (N.=20) and control (N.=21) groups. ESPB was performed under ultrasound guidance with 0.25% bupivacaine (20 mLbilaterally) at T7-T9 levels. The control group received no block. Postoperative analgesia included IVacetaminophen, opioids, alongside fentanyl patient-controlled analgesia. Pain intensity was assessed using Numeric Rating Scale (NRS) at various time intervals. Primary outcome was to compare postoperative opioid consumption levels and secondary outcomes were to evaluate postoperative pain scores, requirement of rescue analgesia, and opioid-related side effects. RESULTS: Patients in ESBP group exhibited lower total fentanyl consumption (P=0.023) and lower meperidine use for rescue analgesia (P=0.001) compared to controls. While static pain scores showed no significant difference, Group ESPB reported lower dynamic pain scores in the immediate postoperative period (P=0.047). The incidence of nausea was lower in Group ESPB (6 vs. 17, P=0.002) with no observed complications. CONCLUSIONS: ESPB displayed promise in effectively managing post-living donor hepatectomy pain, resulting in decreased opioid consumption, improved pain relief, and reduced rescue analgesia requirements. This technique holds potential to enhance recovery and patient satisfaction following donor hepatectomy.
dc.identifier.citationUludağ Yanaral, T., Güngör, H., İnce, A., Yaprak, O., Atalay, Y. O., Çiftçi, B. ... Karaaslan, P. (2024). Ultrasound-guided bilateral erector spinae plane block in the management of postoperative analgesia in living liver donors: a randomized, prospective study. Minerva Anestesiologica, 90(12), 1082-1089. http://dx.doi.org/10.23736/S0375-9393.24.18085-6
dc.identifier.doi10.23736/S0375-9393.24.18085-6
dc.identifier.endpage1089
dc.identifier.issn0375-9393
dc.identifier.issn1827-1596
dc.identifier.issue12
dc.identifier.pmid39630140
dc.identifier.scopus2-s2.0-85216218246
dc.identifier.scopusqualityQ2
dc.identifier.startpage1082
dc.identifier.urihttp://dx.doi.org/10.23736/S0375-9393.24.18085-6
dc.identifier.urihttps://hdl.handle.net/20.500.12511/13246
dc.identifier.volume90
dc.identifier.wosWOS:001371955900001
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorUludağ Yanaral, Tümay
dc.institutionauthorGüngör, Hande
dc.institutionauthorİnce, Ayşe
dc.institutionauthorYaprak, Onur
dc.institutionauthorAtalay, Yunus Oktay
dc.institutionauthorÇiftçi, Bahadır
dc.institutionauthorKaraaslan, Pelin
dc.institutionauthorid0000-0003-3917-8183
dc.institutionauthorid0000-0002-8920-1516
dc.institutionauthorid0000-0003-1941-8290
dc.institutionauthorid0000-0001-9928-9956
dc.institutionauthorid0000-0002-3245-6614
dc.institutionauthorid0000-0002-5273-1871
dc.language.isoen
dc.relation.ispartofMinerva Anestesiologica
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectAcute Pain
dc.subjectAnesthesia
dc.subjectLiver Transplantation
dc.subjectLiving Donors
dc.subjectPain Management
dc.subjectUltrasonography
dc.titleUltrasound-guided bilateral erector spinae plane block in the management of postoperative analgesia in living liver donors: a randomized, prospective study
dc.typeArticle

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