Fetal left ventricular myocardial performance index measured at 11–14 weeks of gestation in fetuses with an increased nuchal translucency

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dc.authorid0000-0002-2257-2355
dc.contributor.authorSezer, Salim
dc.contributor.authorOğlak, Süleyman Cemil
dc.contributor.authorKaya, Başak
dc.contributor.authorBehram, Mustafa
dc.contributor.authorGedik Özköse, Zeynep
dc.contributor.authorSüzen Çaypınar, Sema
dc.contributor.authorAcar, Züat
dc.contributor.authorGezdirici, Alper
dc.contributor.authorBornaun, Helen
dc.date.accessioned2023-05-31T10:49:44Z
dc.date.available2023-05-31T10:49:44Z
dc.date.issued2023
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Kadın Hastalıkları ve Doğum Ana Bilim Dalı
dc.description.abstractObjective: This study aimed to evaluate the effect of an increase in nuchal translucency (NT) thickness on the myocardial performance index (MPI) in fetuses without cardiac anomaly in the first trimester and to determine whether a difference in MPI between those with and without trisomy 21 in these fetuses could be determined. Methods: The study group consisted of 53 pregnancies complicated with increased NT thickness without any associated structural anomalies. Forty-six gestational age-matched pregnant women whose fetuses had normal NT thickness were enrolled as the control group. Results: In the increased NT thickness group, the mean isovolumetric relaxation time (IRT) value (0.050 ± 0.011 s) was significantly higher and the mean ejection time (ET) value (0.149 ± 0.010 s) was significantly lower than those values in the normal NT thickness group (0.045 ± 0.005 and 0.155 ± 0.009 s, p = 0.023 and p = 0.009, respectively). We found a significantly higher mean left MPI value in the increased NT thickness group (0.574 ± 0.153) versus the normal NT thickness group (0.487 ± 0.107, p < 0.001). Within the increased NT thickness group, the mean left MPI value was similar in the fetuses with normal karyotype and those with trisomy 21 (p = 0.419). Conclusion: We demonstrated a significantly greater mean MPI value in the increased NT thickness group than in the normal NT thickness group. Within the increased NT thickness group, no differences in the left MPI value in the fetuses with normal karyotype and the fetuses with trisomy 21 were found.
dc.identifier.citationSezer, S., Oğlak, S. C., Kaya, B., Behram, M., Gedik Özköse, Z., Süzen Çaypınar, S. ... Bornaun, H. (2023). Fetal left ventricular myocardial performance index measured at 11–14 weeks of gestation in fetuses with an increased nuchal translucency. Journal of Obstetrics and Gynaecology Research, 49(4), 1121-1128. https://doi.org/10.1111/jog.15551
dc.identifier.doi10.1111/jog.15551
dc.identifier.endpage1128
dc.identifier.issn1341-8076
dc.identifier.issn1447-0756
dc.identifier.issue4
dc.identifier.pmid36691372
dc.identifier.scopus2-s2.0-85146923216
dc.identifier.scopusqualityQ2
dc.identifier.startpage1121
dc.identifier.urihttps://doi.org/10.1111/jog.15551
dc.identifier.urihttps://hdl.handle.net/20.500.12511/11002
dc.identifier.volume49
dc.identifier.wos000921641000001en_US
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorKaya, Başak
dc.language.isoen
dc.publisherWiley
dc.relation.ispartofJournal of Obstetrics and Gynaecology Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/embargoedAccess
dc.subjectDoppler-Diagnostic
dc.subjectObstetrics
dc.subjectDiagnostic Ultrasound and Prenatal Diagnosis
dc.titleFetal left ventricular myocardial performance index measured at 11–14 weeks of gestation in fetuses with an increased nuchal translucency
dc.typeArticle

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