The effect of chronic swimming exercise and vitamin e supplementation on bone element metabolism in epileptic rats
| dc.authorid | 0000-0002-9752-7508 | |
| dc.contributor.author | Baltacı, Saltuk Buğra | |
| dc.contributor.author | Tutkun, Erkut | |
| dc.contributor.author | Ayyıldız, Mustafa | |
| dc.contributor.author | Ağar, Erdal | |
| dc.contributor.author | Arslan, Gökhan | |
| dc.contributor.author | Moğulkoç, Rasim | |
| dc.contributor.author | Baltacı, Abdülkerim Kasım | |
| dc.date.accessioned | 2024-06-25T12:37:09Z | |
| dc.date.available | 2024-06-25T12:37:09Z | |
| dc.date.issued | 2024 | |
| dc.department | İstanbul Medipol Üniversitesi, Rektörlük, Rejeneratif ve Restoratif Tıp Araştırmaları Merkezi (REMER) | |
| dc.department | İstanbul Medipol Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Fizyoloji Ana Bilim Dalı | |
| dc.description.abstract | Introduction: This study aimed to investigate the effects of chronic swimming exercise and vitamin E administration on elemental levels in the bone tissue of epileptic rats. Methods: Forty-eight rats were divided into six groups: Control, Swimming, Swimming + vitamin E, Swimming + Epilepsy, Swimming + Epilepsy + vitamin E, and Epilepsy. Vitamin E was administered to the animals chronically by gavage at a dose of 500 mg/kg every other day for 3 months. Epileptiform activity was induced with penicillin in animals 24 hours after the last vitamin E intake. The exercise program consisted of daily 30-minute swimming sessions. At the end of the treatment period, the levels of calcium, chromium, copper, iron, magnesium, manganese, lead, and zinc (µg/gram tissue) in bone tissue samples were measured using an atomic emission device. Results: The results showed that all epileptic groups had significantly lower bone chromium levels compared to the control groups (p<0.05). The epileptic, and epileptic swimming groups had the lowest levels of bone calcium, magnesium, and zinc (p<0.05). Vitamin E administration resulted in a significant increase in bone calcium, magnesium, and zinc levels in the epileptic swimming group with vitamin E compared to the epileptic and epileptic swimming groups. (p<0.05). Conclusion: The findings of the study show that the administration of vitamin E improves calcium, magnesium, and zinc metabolism in the deteriorated bone tissue of the epileptic rat model. | |
| dc.identifier.citation | Baltacı, S. B., Tutkun, E., Ayyıldız, M., Ağar, E., Arslan, G., Moğulkoç, R. ... Baltacı, A. K. (2024). The effect of chronic swimming exercise and vitamin e supplementation on bone element metabolism in epileptic rats. Archives of Neuropsychiatry, 61(2), 113-118. http://dx.doi.org/10.29399/npa.28495 | |
| dc.identifier.doi | 10.29399/npa.28495 | |
| dc.identifier.endpage | 118 | |
| dc.identifier.issn | 1300-0667 | |
| dc.identifier.issn | 1309-4866 | |
| dc.identifier.issue | 2 | |
| dc.identifier.pmid | 38868851 | |
| dc.identifier.scopus | 2-s2.0-85196398472 | |
| dc.identifier.scopusquality | Q3 | |
| dc.identifier.startpage | 113 | |
| dc.identifier.uri | http://dx.doi.org/10.29399/npa.28495 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12511/12648 | |
| dc.identifier.volume | 61 | |
| dc.identifier.wos | 001244741800004 | en_US |
| dc.identifier.wosquality | Q4 | |
| dc.indekslendigikaynak | Web of Science | |
| dc.indekslendigikaynak | Scopus | |
| dc.indekslendigikaynak | PubMed | |
| dc.institutionauthor | Baltacı, Saltuk Buğra | |
| dc.language.iso | en | |
| dc.relation.ispartof | Archives of Neuropsychiatry | en_US |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | |
| dc.rights | info:eu-repo/semantics/openAccess | |
| dc.subject | Bone Elemental Metabolism | |
| dc.subject | Epilepsy | |
| dc.subject | Rat | |
| dc.subject | Swimming Exercise | |
| dc.subject | Vitamin E | |
| dc.title | The effect of chronic swimming exercise and vitamin e supplementation on bone element metabolism in epileptic rats | |
| dc.title.alternative | Epileptik sıçanlarda kronik yüzme egzersizi ve E vitamini desteğinin kemik element metabolizması üzerine etkisi | |
| dc.type | Article |
