Predictors of right ventricular systolic dysfunction in non-ischemic dilated cardiomyopathy: An echocardiographic study

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dc.contributor.authorKaraca, Oğuz
dc.contributor.authorAvcı, Anıl
dc.contributor.authorGüler Babür, Gamze
dc.contributor.authorOmaygenç, Onur
dc.contributor.authorÇakal, Beytullah
dc.contributor.authorGüneş, Hacı Murat
dc.contributor.authorAlizade, Elnur
dc.contributor.authorEsen, Ali Metin
dc.contributor.authorBarutcu, İrfan
dc.contributor.authorBoztosun, Bilal
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T19:56:30Z
dc.date.available10.07.201910:49:13
dc.date.available2019-07-10T19:56:30Z
dc.date.issued2016
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Kardiyoloji Ana Bilim Dalı
dc.descriptionWOS: 000372153000004
dc.description.abstractBackground: Right Ventricular (RV) functions are known to have an impact on determining the prognosis of patients with Non-Ischemic Dilated Cardiomyopathy (NICMP). Objectives: This study aimed to investigate the echocardiographic determinants of RV systolic dysfunction in patients with NICMP. Patients and Methods: This cross-sectional study was conducted on 79 patients with angiographically normal coronary arteries (mean age: 50.5 +/- 12, mean Ejection Fraction (EF): 31 +/- 4%) selected through purposive sampling The patients were divided into two groups based on their RV systolic function determined by tissue Doppler systolic velocities (RV-Sm): group A (RV-Sm >= 10 cm/s, N = 48) and group B (RV-Sm <10 cm/s, N = 31). The two groups were compared regarding clinical, demographic, and echocardiographic variables using independent t-test and chi-square test. Results: The patients with RV systolic dysfunction were found to have higher Brain Natriuretic Peptide (BNP) values (P = 0.006) and worse functional status (New York Heart Association (NYHA) III-IV, P = 0.04) compared to group A. Besides, univariate analysis of the echocardiographic parameters revealed that the patients in group B had significantly (all P values <0.05) higher Left Atrial Volume Index (LAVI), higher degree of left ventricular diastolic dysfunction (represented by LV-E/Em), higher degree of Functional Mitral Regurgitation (FMR), higher estimated Pulmonary Artery Systolic Pressure (PASP), and higher degree of RV diastolic dysfunction (represented by RV-E/Em) Moreover, multivariate logistic regression analysis showed that severe FMR (P = 0.006) and RV-E/Em (P = 0.016) predicted RV systolic dysfunction independently. Conclusions: Advanced FMR and worse RV diastolic functions emerged as the independent predictors of RV systolic dysfunction in NICMP correlating to functional status and BNP levels.
dc.identifier.citationKaraca, O., Avcı, A., Güler Babür, G., Omaygenç, O., Çakal, B., Güneş, H. M. ... Boztosun, B. (2016). Predictors of right ventricular systolic dysfunction in non-ischemic dilated cardiomyopathy: An echocardiographic study. International Cardiovascular Research Journal, 10(1), 10-23. https://dx.doi.org/10.17795/icrj-10(1)17
dc.identifier.doi10.17795/icrj-10(1)17
dc.identifier.endpage23
dc.identifier.issn2251-9130
dc.identifier.issn2251-9149
dc.identifier.issue1
dc.identifier.scopusqualityQ3
dc.identifier.startpage17
dc.identifier.urihttps://dx.doi.org/10.17795/icrj-10(1)17
dc.identifier.urihttps://hdl.handle.net/20.500.12511/2726
dc.identifier.volume10
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherShiraz Univ Medical Sciences, Cardiovascular Research Center
dc.relation.ispartofInternational Cardiovascular Research Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectDilated Cardiomyopathy
dc.subjectRight Ventricle
dc.subjectEchocardiography
dc.titlePredictors of right ventricular systolic dysfunction in non-ischemic dilated cardiomyopathy: An echocardiographic study
dc.typeArticle

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