Effect of non-surgical periodontal treatment on lipoxin A4 levels in periodontitis patients

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dc.authorid0000-0001-5166-2109
dc.contributor.authorTürkmen, Emrah
dc.contributor.authorGökmenoğlu, Ceren
dc.contributor.authorKara, Cankat
dc.contributor.authorÖngöz Dede, Figen
dc.contributor.authorErbak Yılmaz, Huriye
dc.contributor.authorÇanakçı, Varol
dc.date.accessioned2022-03-28T06:33:57Z
dc.date.available2022-03-28T06:33:57Z
dc.date.issued2022
dc.departmentİstanbul Medipol Üniversitesi, Diş Hekimliği Fakültesi, Periodontoloji Ana Bilim Dalı
dc.description.abstractThe aim of this study was to determine the lipoxin A4 (LXA4) in gingival crevicular fluid (GCF) and saliva in chronic periodontitis (CP) patients before and after non-surgical periodontal treatment (NSPT). A total of twenty subjects, ten patients with CP and ten healthy individuals were included in this study. Clinical measurements, GCF and saliva samples were obtained at the beginning and one month after NSPT. GCF and salivary LXA4 were investigated by ELISA. Salivary LXA4 were significantly higher in CP than in healthy subjects (p [removed] 0.05). GCF LXA4 were lower in CP and decreased after NSPT, but these differences were not significant (p > 0.05). However, GCF LXA4 in post-treatment CP group were significantly lower than in healthy subjects (p < 0.05). Negative correlation was found between probing depth and GCF LXA4 in CP group (r = ?0.717; p < 0.05). Within the limitations of this study, LXA4 might have a potential role in both the pathogenesis of periodontitis and the healing process.
dc.identifier.citationTürkmen, E., Gökmenoğlu, C., Kara, C., Öngöz Dede, F., Erbak Yılmaz, H. ve Çanakçı, V. (2022). Effect of non-surgical periodontal treatment on lipoxin A4 levels in periodontitis patients. Comptes Rendus de L'Academie Bulgare des Sciences, 75(2), 287-294. https://doi.org/10.7546/CRABS.2022.02.15
dc.identifier.doi10.7546/CRABS.2022.02.15
dc.identifier.endpage294
dc.identifier.issn1310-1331
dc.identifier.issue2
dc.identifier.scopus2-s2.0-85126475796
dc.identifier.scopusqualityQ3
dc.identifier.startpage287
dc.identifier.urihttps://doi.org/10.7546/CRABS.2022.02.15
dc.identifier.urihttps://hdl.handle.net/20.500.12511/9178
dc.identifier.volume75
dc.identifier.wos000772654200015en_US
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.institutionauthorTürkmen, Emrah
dc.language.isoen
dc.publisherAcademic Publishing House
dc.relation.ispartofComptes Rendus de L'Academie Bulgare des Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectGingival Crevicular Fluid
dc.subjectLipoxins
dc.subjectPeriodontal Treatment
dc.subjectPeriodontitis
dc.subjectSaliva
dc.titleEffect of non-surgical periodontal treatment on lipoxin A4 levels in periodontitis patients
dc.typeArticle

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