Long term predictive ability of preoperative retinal nerve fiber layer thickness in visual prognosis after chiasmal decompression surgery

Basit Öğe Kaydı
dc.authorid0000-0002-8047-5553
dc.contributor.authorMangan, Mehmet Serhat
dc.contributor.authorGelegen, Erdem
dc.contributor.authorBaşerer, Tahire
dc.contributor.authorGazio?lu, Nurperi
dc.contributor.authorAras, Cengiz
dc.date.accessioned2021-06-18T05:59:20Z
dc.date.available2021-06-18T05:59:20Z
dc.date.issued2021
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Göz Hastalıkları Ana Bilim Dalı
dc.description.abstractObjective: To investigate the relationship between preoperative retinal nerve fiber layer (RNFL) thickness and the recovery of visual field (VF) and visual acuity (VA) 1 year after surgery in chiasmal compression patients presenting with visual impairment. Patients and methods: Twenty-nine eyes of 16 patients with chiasmal compression and 14 eyes of 14 control subjects were enrolled. All patients undergoing chiasmal decompression surgery via a transsphenoidal approach were prospectively evaluated before and 1 year after surgery with best corrected visual acuity (BCVA, logMAR), mean deviation (MD) value with standard automated perimetry (SAP) and RNFL thickness with optical coherence tomography. Eyes with chiasmal compression were divided into two groups according to the mean preoperative RNFL thickness: ? 100 µm (Group 1) and < 100 µm (Group 2). The relationship between the mean preoperative RNFL thickness and visual prognosis parameters (VF, VA) was analyzed. Results: The mean preoperative RNFL thickness was 115.92 ± 8.97 µm, 84.0 ± 8.85 µm, and 114.21 ± 7.75 µm in Group 1 (n = 15 eyes), Group 2 (n = 14 eyes) and the control group (n = 14 eyes), respectively. The mean preoperative BCVA was 0.15 ± 0.3 in Group 1, and 0.41 ± 0.39 in Group 2. The mean BCVA increased to 0.03 ± 0.1 in Group 1 in the postoperative period but did not change in Group 2. MD value was ? 6.10 ± 5.54 in the preoperative period and ? 2.59 ± 2.23 in the postoperative period for Group 1 (p = 0.014), while it was ? 18.97 ± 4.14 in the preoperative period and ? 18.57 ± 4.51 in the postoperative period in Group 2 (p = 0.24). Conclusions: This study suggests that lower mean preoperative RNFL thickness was associated with poorer long-term visual prognosis. Preoperative RNFL thickness measurements may be helpful in predicting the recovery of VF and VA after decompression surgery in patients with chiasmal lesion presenting with visual impairment.
dc.identifier.citationMangan, M. S., Gelegen, E., Başerer, T., Gazio?lu, N. ve Aras, C. (2021). Long term predictive ability of preoperative retinal nerve fiber layer thickness in visual prognosis after chiasmal decompression surgery. Clinical Neurology and Neurosurgery, 207. https://dx.doi.org/10.1016/j.clineuro.2021.106734
dc.identifier.doi10.1016/j.clineuro.2021.106734
dc.identifier.issn0303-8467
dc.identifier.issn1872-6968
dc.identifier.scopusqualityQ2
dc.identifier.urihttps://dx.doi.org/10.1016/j.clineuro.2021.106734
dc.identifier.urihttps://hdl.handle.net/20.500.12511/7212
dc.identifier.volume207
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherElsevier B.V.
dc.relation.ispartofClinical Neurology and Neurosurgeryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/embargoedAccess
dc.subjectChiasmal Compression
dc.subjectOptical Coherence Tomography
dc.subjectRetinal Nerve Fiber Layer Thickness
dc.subjectVisual Acuity
dc.subjectVisual Field
dc.subjectVisual Recovery
dc.titleLong term predictive ability of preoperative retinal nerve fiber layer thickness in visual prognosis after chiasmal decompression surgery
dc.typeArticle

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim Yok
İsim:
Aras-Cengiz-2021.pdf
Boyut:
368.55 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin / Full Text
İndir
Lisans paketi
Listeleniyor 1 - 1 / 1
Küçük Resim Yok
İsim:
license.txt
Boyut:
1.44 KB
Biçim:
Item-specific license agreed upon to submission
Açıklama:
İndir

Koleksiyon

Makale Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu