Dry eye assessment in patients with vitamin D deficiency

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dc.authorid0000-0002-5079-4713
dc.authorid0000-0001-9829-7268
dc.authorid0000-0001-8954-5055
dc.authorid0000-0002-9815-1848
dc.authorid0000-0003-0668-3749
dc.contributor.authorDemirci, Göktuğ
dc.contributor.authorErdur, Sevil Karaman
dc.contributor.authorÖzsütçü, Mustafa
dc.contributor.authorEliaçık, Mustafa
dc.contributor.authorÖlmüşçelik, Oktay
dc.contributor.authorAydın, Rukiye
dc.contributor.authorKocabora, Mehmet Selim
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T19:50:12Z
dc.date.available10.07.201910:49:13
dc.date.available2019-07-10T19:50:12Z
dc.date.issued2018
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Göz Hastalıkları Ana Bilim Dalı
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıkları Ana Bilim Dalı
dc.descriptionWOS: 000457837000011
dc.descriptionPubMed ID: 27660921
dc.description.abstractObjectives: The aim of this study was to evaluate tear film function in patients with vitamin D deficiency. Methods: In a single center, 60 eyes of 30 patients with vitamin D deficiency (group 1), and 60 eyes of 30 healthy individuals (group 2) were evaluated using the Ocular Surface Disease Index (OSDI) questionnaire, Schirmer I test, tear break-up time (TBUT), scoring of ocular surface fluorescein staining using a modified Oxford scale, and tear osmolarity. Results: Tear osmolarity values, OSDI, and Oxford scale scores were significantly higher in group 1 (309 +/- 9 mOsm/L, 35.78 +/- 21.44 and 1.3 +/- 0.9, respectively) compared with group 2 (295610 mOsm/L, 18.69 +/- 17.21 and 0.4 +/- 0.8, respectively) (P<0.001 for all). Schirmer I test and TBUT results in group 1 (8.5 +/- 3.7 mm and 8.7 +/- 0.6 sec, respectively) were significantly lower compared with group 2 (16.6 +/- 2.4 and 18.1 +/- 0.5, respectively) (P<0.001 for all). Conclusions: This study demonstrates that vitamin D deficiency is associated with tear hyperosmolarity and tear film dysfunction. Patients with vitamin D deficiency may be prone to dry eye.
dc.identifier.citationDemirci, G., Karaman Erdur, S., Özsütçü, M., Eliaçık, M., Ölmüşçelik, O., Aydın, R. ... Kocabora, M. S. (2018). Dry eye assessment in patients with vitamin D deficiency. Eye and Contact Lens, 44(Supplement: 1), S62-S65. https://dx.doi.org/10.1097/ICL.0000000000000325
dc.identifier.doi10.1097/ICL.0000000000000325
dc.identifier.endpageS65
dc.identifier.issn1542-2321
dc.identifier.issn1542-233X
dc.identifier.issueSupplement: 1
dc.identifier.scopusqualityQ2
dc.identifier.startpageS62
dc.identifier.urihttps://dx.doi.org/10.1097/ICL.0000000000000325
dc.identifier.urihttps://hdl.handle.net/20.500.12511/1911
dc.identifier.volume44
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherLippincott Williams and Wilkins
dc.relation.ispartofEye and Contact Lensen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectDry Eye
dc.subjectVitamin D Deficiency
dc.subjectSchirmer Test
dc.subjectTear Osmolarity
dc.titleDry eye assessment in patients with vitamin D deficiency
dc.typeArticle

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