Corneal biomechanical properties in obstructive sleep apnea syndrome

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dc.authorid0000-0003-2312-2521
dc.authorid0000-0001-9829-7268
dc.authorid0000-0003-0668-3749
dc.contributor.authorDikkaya, Funda
dc.contributor.authorYıldırım, Rengin
dc.contributor.authorKaraman Erdur, Sevil
dc.contributor.authorBenbir, Gülçin
dc.contributor.authorAydın, Rukiye
dc.contributor.authorKaradeniz, Derya
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T19:50:01Z
dc.date.available10.07.201910:49:13
dc.date.available2019-07-10T19:50:01Z
dc.date.issued2018
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Göz Hastalıkları Ana Bilim Dalı
dc.descriptionWOS: 000457840400061
dc.descriptionPubMed ID: 29420326
dc.description.abstractObjectives: To investigate the corneal biomechanical properties and anterior segment parameters in patients with obstructive sleep apnea syndrome (OSAS). Methods: Fifty-four eyes of 54 patients with OSAS and 20 eyes of 20 healthy subjects were included. Patients with mild and moderate OSAS (Respiratory Disturbance Index [RDI] <30) enrolled in group 1, those with severe OSAS (RDI>= 30) in group 2 and controls in group 3. Corneal biomechanical properties including corneal hysteresis (CH), corneal resistance factor (CRF), Goldmann-correlated intraocular pressure (IOPg), and corneal-compensated intraocular pressure (IOPcc) were measured with ocular response analyzer. Maximum (Kmax), minimum (Kmin), and mean simulated (SimKm) keratometry values, corneal astigmatism (CA), and central corneal thickness (CCT) were evaluated with Pentacam Scheimpflug imaging. Results: The mean CH and CRF were significantly lower in group 2. The mean CH was 10.9 +/- 1.4 mm Hg in group 1,10.1 +/- 1.1 mm Hg in group 2, and 12.1 +/- 1.2 mm Hg in group 3 (P<0.001). The mean CRF was 11.1 +/- 1.8 mm Hg in group 1, 9.9 +/- 1.1 mm Hg in group 2, and 12.2 +/- 1.2 mm Hg in group 3 (P<0.001). The CH and CRF values were similar between the groups 1 and 3 (P = 0.867 and P = 0.743). Corneal-compensated intraocular pressure, IOPg, Kmax, Kmin, SimKm, CA, and CCT values were not statistically different among the three groups. Conclusions: Patients with severe OSAS had lower CH and CRF values. The lower CH and CRF values in the severe group were possibly related to changes of the structural properties in the cornea.
dc.identifier.citationDikkaya, F., Yıldırım, R., Karaman Erdur, S., Benbir, G., Aydın, R. ve Karadeniz, D. (2018). Corneal biomechanical properties in obstructive sleep apnea syndrome. Eye & Contact Lens-Science and Clinical Practice, 44(Supplement: 2), S361-S364. https://dx.doi.org/10.1097/ICL.0000000000000489
dc.identifier.doi10.1097/ICL.0000000000000489
dc.identifier.endpageS364
dc.identifier.issn1542-2321
dc.identifier.issn1542-233X
dc.identifier.issueSupplement: 2
dc.identifier.scopusqualityQ2
dc.identifier.startpageS361
dc.identifier.urihttps://dx.doi.org/10.1097/ICL.0000000000000489
dc.identifier.urihttps://hdl.handle.net/20.500.12511/1852
dc.identifier.volume44
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherLippincott Williams & Wilkins
dc.relation.ispartofEye & Contact Lens-Science and Clinical Practiceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/embargoedAccess
dc.subjectCorneal Biomechanical Properties
dc.subjectCorneal Hysteresis
dc.subjectCorneal Resistance Factor
dc.subjectObstructive Sleep Apnea Syndrome
dc.subjectAnterior Segment Parameters
dc.titleCorneal biomechanical properties in obstructive sleep apnea syndrome
dc.typeArticle

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