Five compelling UTI questions after kidney transplant

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dc.contributor.authorAydın, Selda
dc.contributor.authorPatil, Abhijit
dc.contributor.authorDesai, Mahesh
dc.contributor.authorSimforoosh, Nasser
dc.date.accessioned2020-11-30T12:27:17Z
dc.date.available2020-11-30T12:27:17Z
dc.date.issued2020
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Enfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Ana Bilim Dalı
dc.description.abstractPurpose Urinary tract infection (UTI) is the most common bacterial infection among infectious complications in kidney transplant recipients (KTR). After transplantation, infections can result from surgical complications, donor-derived infections, pre-existing recipient infections, and nosocomial infections. Post-transplant infection is still a major cause of morbidity, mortality, graft dysfunction and rejection. In this paper, we aimed to review a few compelling questions in kidney transplantation (KTX). Methods To identify relevant clinical questions regarding KTX and UTI a meeting was conducted among physicians involved in the KT program in our hospital. After discussion, several clinically relevant questions related to UTI after KTX. The 5 first rated in importance were judged generalizable to other clinical settings and selected for the purposes of this review. Results Nearly half of the patients present in the first three months of transplant with UTI. The most common uropathogens in post-transplant UTIs are Escherichia coli, Klebsiella pneumoniae, and Enterococcus faecalis. Risk factors for UTI include female sex, advanced age, recurrent UTI before transplant, prolonged urethral catheterization, delayed graft function, and cadaveric kidney transplant. Conclusion The incidence of post-transplant UTI is similar in both developed and developing countries. E.coli is the most common pathogen in most of studies. Cadaveric donor and post-dialysis transplantation are defined as independent risk factors for post-transplant UTI. Further studies are still required to identify risk factors after kidney transplantation and UTI's importance for graft function and patient outcome.
dc.identifier.citationAydın, S., Patil, A., Desai, M. ve Simforoosh, N. (2020). Five compelling UTI questions after kidney transplant. World Journal of Urology, 38(11), 2733-2742. https://dx.doi.org/10.1007/s00345-020-03173-4
dc.identifier.doi10.1007/s00345-020-03173-4
dc.identifier.endpage2742
dc.identifier.issn0724-4983
dc.identifier.issn1433-8726
dc.identifier.issue11
dc.identifier.scopusqualityQ1
dc.identifier.startpage2733
dc.identifier.urihttps://dx.doi.org/10.1007/s00345-020-03173-4
dc.identifier.urihttps://hdl.handle.net/20.500.12511/6059
dc.identifier.volume38
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherSpringer
dc.relation.ispartofWorld Journal of Urologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/embargoedAccess
dc.subjectUrinary Tract Infection
dc.subjectKidney Transplantation
dc.subjectCadaveric Donor
dc.subjectPre-Emptive Transplantation
dc.titleFive compelling UTI questions after kidney transplant
dc.typeArticle

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