Ischemia-modified albumin levels in patients with bell's palsy

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dc.authorid0000-0003-0606-864X
dc.authorid0000-0003-2350-6381
dc.authorid0000-0002-0675-1839
dc.contributor.authorCırık, Ahmet Adnan
dc.contributor.authorEvcimik, Muhammed Fatih
dc.contributor.authorÜlfer, Gözde
dc.contributor.authorYigitbaşı, Türkan
dc.contributor.authorAktaş, Öztürk
dc.date.accessioned2022-10-20T13:56:38Z
dc.date.available2022-10-20T13:56:38Z
dc.date.issued2022
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Kulak Burun Boğaz Hastalıkları Ana Bilim Dalı
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Tıbbi Biyokimya Ana Bilim Dalı
dc.description.abstractBackground: Although several causes have been regarded as possible including viral, autoimmune, inflammatory, and vascular ischemia, the accurate etiology and pathophysiology of Bell's palsy (BP) remain unclear. The aim of the present article was to determine whether serum levels of ischemia-modified albumin (IMA) are associated with BP and if there is a posttreatment change in IMA levels. Materials and Methods: This was a prospective study enrolling 23 patients (10 males and 13 females; mean age: 44.71 +/- 16.72 years; and range, 20-57 years) and 23 healthy individuals (12 males and 11 females; mean age: 37.91 +/- 9.16 years; and range, 9-73 years) as the control group. Blood samples were obtained from the antecubital vein from all of the volunteers. Albumin cobalt binding test was used to obtain the IMA levels. Results: The mean IMA level was 0.38 +/- 0.06 absorbance units in the study group at the time of diagnosis, 0.35 +/- 0.07 absorbance units at the posttreatment period, and 0.35 +/- 0.06 absorbance units in the control group. IMA levels of patients in posttreatment period were lower than the onset of illness. The result was statistically significant (P = 0.01). Conclusion: The data demonstrate that IMA decreased in BP with treatment. This is a preliminary study and we could not obtain results that clearly support the ischemic hypothesis of pathogenesis of BP; we think it gives an idea for further studies.
dc.identifier.citationCırık, A. A., Evcimik, M. F., Ülfer, G., Yigitbaşı, T. ve Aktaş, Ö. (2022). Ischemia-modified albumin levels in patients with bell's palsy. Indian Journal of Otology, 28(2), 139-143. https://doi.org/10.4103/indianjotol.indianjotol_4_22
dc.identifier.doi10.4103/indianjotol.indianjotol_4_22
dc.identifier.endpage143
dc.identifier.issn0971-7749
dc.identifier.issn2249-9520
dc.identifier.issue2
dc.identifier.scopus2-s2.0-85139396148
dc.identifier.scopusqualityQ4
dc.identifier.startpage139
dc.identifier.urihttps://doi.org/10.4103/indianjotol.indianjotol_4_22
dc.identifier.urihttps://hdl.handle.net/20.500.12511/9863
dc.identifier.volume28
dc.identifier.wos000864595300009en_US
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.institutionauthorEvcimik, Muhammed Fatih
dc.institutionauthorÜlfer, Gözde
dc.institutionauthorYiğitbaşı, Türkan
dc.language.isoen
dc.publisherWolters Kluwer Medknow Publications
dc.relation.ispartofIndian Journal of Otologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectBell's Palsy
dc.subjectIdiopathic Facial Paralysis
dc.subjectIschemia-Modified Albumin
dc.titleIschemia-modified albumin levels in patients with bell's palsy
dc.typeArticle

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