Carotid artery plaque structure in the context of symptomatic/asymptomatic nature of carotid artery stenosis
| dc.authorid | 0000-0001-9919-8392 | |
| dc.authorid | 0000-0001-6643-9364 | |
| dc.contributor.author | Öztaş, Didem Melis | |
| dc.contributor.author | Tanören Bilen, Bukem | |
| dc.contributor.author | Türker Şener, Leyla | |
| dc.contributor.author | Beyaz, Metin Onur | |
| dc.contributor.author | Ulukan, Mustafa Özer | |
| dc.contributor.author | Ünal, Orçun | |
| dc.contributor.author | Ünlü, Mehmet Burçin | |
| dc.contributor.author | Reis, Paulo Eduardo Ocke | |
| dc.contributor.author | Uğurlucan, Murat | |
| dc.date.accessioned | 2021-09-23T07:37:40Z | |
| dc.date.available | 2021-09-23T07:37:40Z | |
| dc.date.issued | 2021 | |
| dc.department | İstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Kalp ve Damar Cerrahisi Ana Bilim Dalı | |
| dc.description.abstract | Objective: In this paper, we examined the relationship between atherosclerotic plaque characteristics and symptomatic carotid artery disease. Material and methods: Twenty-two patients who underwent carotid endarterectomy were enrolled into the study. Thirteen patients were male and remaining 9 patients were female. The mean age was 60.2 +/- 9.6 years. The carotid artery stenosis ranged between 75% and 99%. Eight patients were asymptomatic and remaining 14 patients were symptomatic. Ten patients suffered stroke. One of them had recurrent transient ischemic attacks, 4 patients had dizziness, and one of them had amaurosis fugax. The extracted plaques were evaluated by scanning acoustic microscopy (SAM) and micro-computerized tomography (micro-CT). Results: Smaller acoustic impedance values that reveal collagen-rich plaque formation were detected in patients who had stroke, while higher acoustic impedance values that reveal calcium-rich plaque formation were detected in the asymptomatic patients' plaques. Conclusions: Determination of plaque characteristics with modern radiographic techniques, rather than relying on the degree of stenosis in patients with carotid artery disease, may be helpful to discriminate patients requiring intervention. | |
| dc.description.abstract | Cíl: V této studii jsme zkoumali vztah mezi charakteristikami aterosklerotického plátu a symptomatick?m posti?ením karotick?ch tepen. Materiál a metody: Do studie bylo za?azeno 22 pacient? (13 mu?? a 9 ?en pr?m?rného v?ku 60,2 ± 9,6 roku) po endarterektomii karotick?ch tepen. Záva?nost stenózy karotické tepny se pohybovala v rozmezí 75 % a? 99 %. Osm pacient? bylo asymptomatick?ch a zb?vajících 14 symptomatick?ch. Deset pacient? prod?lalo cévní mozkovou p?íhodu. V anamnéze m?l jeden pacient recidivující tranzitorní ischemické p?íhody, ?ty?i pacienti uvád?li presynkopální stav a u jednoho byla stanovena diagnóza amaurosis fugax. Odstran?né pláty byly vyšet?eny skenující akustickou mikroskopií (scanning acoustic microscopy, SAM) a mikrov?po?etní tomografi í (micro-computerized tomography, micro-CT). V?sledky: U pacient? po cévní mozkové p?íhod? byly nalezeny ni?ší hodnoty akustické impedance ukazující na tvorbu plát? s vysok?m obsahem kolagenu, zatímco u asymptomatick?ch pacient? byly vyšší hodnoty akustické impedance spojeny s tvorbou plát? bohat?ch na vápník. Záv?ry: Spíše ne? spoléhání se na záva?nost stenózy u pacient? s posti?ením karotick?ch tepen m??e p?i vyhledávání pacient? vy?adujících intervenci napomáhat ur?ení charakteristik plát? moderními radiografi ck?mi metodami. | |
| dc.description.sponsorship | Türkiye Cumhuriyeti Kalkınma Bakanlığı | en_US |
| dc.identifier.citation | Öztaş, D. M., Tanören Bilen, B., Türker Şener, L., Beyaz, M. O., Ulukan, M. Ö., Ünal, O. ... Uğurlucan, M. (2021). Carotid artery plaque structure in the context of symptomatic/asymptomatic nature of carotid artery stenosis. Cor et Vasa, 63(4), 459-465. https://dx.doi.org/10.33678/cor.2021.027 | |
| dc.identifier.doi | 10.33678/cor.2021.027 | |
| dc.identifier.endpage | 465 | |
| dc.identifier.issn | 0010-8650 | |
| dc.identifier.issn | 1803-7712 | |
| dc.identifier.issue | 4 | |
| dc.identifier.scopusquality | Q4 | |
| dc.identifier.startpage | 459 | |
| dc.identifier.uri | https://dx.doi.org/10.33678/cor.2021.027 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12511/8281 | |
| dc.identifier.volume | 63 | |
| dc.identifier.wosquality | N/A | |
| dc.indekslendigikaynak | Web of Science | |
| dc.indekslendigikaynak | Scopus | |
| dc.language.iso | en | |
| dc.publisher | Czech Society of Cardiology and Czech Society for Cardiovascular Surgery | |
| dc.relation.ispartof | Cor et Vasa | en_US |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | |
| dc.rights | info:eu-repo/semantics/openAccess | |
| dc.subject | Atherosclerotic Plaque | |
| dc.subject | Characteristics | |
| dc.subject | Carotid Artery Stenosis | |
| dc.subject | Symptomatic Disease | |
| dc.subject | Charakteristiky Aterosklerotického | |
| dc.subject | Plátu | |
| dc.subject | Stenóza Karotické Tepny | |
| dc.subject | Symptomatické Onemocn?ní | |
| dc.title | Carotid artery plaque structure in the context of symptomatic/asymptomatic nature of carotid artery stenosis | |
| dc.type | Article |
