Maternal monosodium glutamate intake influences the learning ability of the offsprinof sprague dawley rats

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dc.contributor.authorÜn, İlyas
dc.contributor.authorBüyükuslu, Nihal
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T19:36:11Z
dc.date.available10.07.201910:49:14
dc.date.available2019-07-10T19:36:11Z
dc.date.issued2018
dc.departmentİstanbul Medipol Üniversitesi, Sağlık Bilimleri Fakültesi, Beslenme ve Diyetetik Bölümü
dc.description.abstractObjectives: Monosodium glutamate (MSG) is one of the most widely consumed food additives. We aimed to identify the effects of maternal MSG intake on off-spring’s learning ability in rats.Patients and Methods: Among thirty female rats, ten control rats were fed by standart diet. Twenty rats were applied 4 mg/g.body weight for 3 weeks and then divided into group I (exposed MSG during pregnancy and lactation) and group II (no MSG). Pups had no MSG at any stage. The adult rats and the pups were applied Barnes maze to test learning ability.Results: Barnes maze test resulted that the learning ability for offspring of MSG treated mother rats decreased in the order of control > maternal MSG intake for 3 weeks before mating > additional maternal MSG intake during pregnancy and lactation. Conclusion: In conclusion maternal MSG intake increased the duration of trial and the number of false trial of offspring in Sprague Dawley rats.
dc.identifier.citationÜn, İ. ve Büyükuslu, N. (2018). Maternal monosodium glutamate intake influences the learning ability of the offsprinof sprague dawley rats. Acta Pharmaceutica Sciencia, 56(4), 107-118. https://dx.doi.org/10.23893/1307-2080.APS.05628
dc.identifier.doi10.23893/1307-2080.APS.05628
dc.identifier.endpage118
dc.identifier.issn1307-2080
dc.identifier.issue4
dc.identifier.scopusqualityQ4
dc.identifier.startpage107
dc.identifier.urihttps://hdl.handle.net/20.500.12511/1088
dc.identifier.urihttps://dx.doi.org/10.23893/1307-2080.APS.05628
dc.identifier.volume56
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherİstanbul Medipol University
dc.relation.ispartofActa Pharmaceutica Scienciaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectBarnes Maze
dc.subjectLearning Ability
dc.subjectMemory
dc.subjectMonosodium Glutamate
dc.subjectSprague Dawley Rats
dc.titleMaternal monosodium glutamate intake influences the learning ability of the offsprinof sprague dawley rats
dc.typeArticle

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