Remembering the Occam’s Razor: Could simple electrocardiographic findings provide relevant predictions for current hemodynamic criteria of pulmonary hypertension?

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dc.authorid0000-0001-6560-6503
dc.contributor.authorTokgöz, Hacer Ceren
dc.contributor.authorÖcal, Bahadır Erdem
dc.contributor.authorErkuş, Yiğit Cengiz
dc.contributor.authorTanyeri Üzel, Seda
dc.contributor.authorKültürsay, Barkın
dc.contributor.authorTosun, Ayhan
dc.contributor.authorKeskin, Berhan
dc.contributor.authorHakgör, Aykun
dc.contributor.authorSırma, Dicle
dc.contributor.authorBuluş, Çağdaş
dc.contributor.authorKaragöz, Ali
dc.contributor.authorTanboğa, İbrahim Halil
dc.contributor.authorKülahçıoğlu, Şeyhmus
dc.contributor.authorBayram, Zübeyde
dc.contributor.authorSekban, Ahmet
dc.contributor.authorÖzdemir, Nihal
dc.contributor.authorKaymaz, Cihangir
dc.date.accessioned2023-11-27T08:11:49Z
dc.date.available2023-11-27T08:11:49Z
dc.date.issued2023
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Kardiyoloji Ana Bilim Dalı
dc.description.abstractBackground: We evaluated the predictive value of electrocardiographic (ECG) findings for pulmonary hemodynamics assessed by right heart catheterization (RHC). Methods: Our study population comprised 562 retrospectively evaluated patients who underwent RHC between 2006 and 2022. Correlations between ECG measures and pulmonary arterial systolic and mean pressures (PASP and PAMP) and pulmonary vascular resistance (PVR) were investigated. Moreover, receiver operating characteristic (ROC) curve analysis assessed the predictive value of ECG for pulmonary hypertension (PH) and precapillary PH. Results: The P-wave amplitude (Pwa) and R/S ratio (r) in V1 and V2, Ra in augmented voltage right (aVR), right or indeterminate axis, but not P wave duration (Pwd) or right bundle branch block (RBBB) significantly correlated with PASP, PAMP, and PVR (P < .001 for all). The partial R2 analysis revealed that amplitude of R wave (Ra) in aVR, R/Sr in V1 and V2, QRS axis, and Pwa added to the base model provided significant contributions to variance for PASP, PAMP, and PVR, respectively. The Pwa > 0.16 mV, Ra in aVR > 0.05 mV, QRS axis > 100° and R/Sr in V1 > 0.9 showed the highest area under curve (AUC) values for PAMP > 20 mm Hg. Using the same cutoff value, Ra in aVR, Pwa, QRS axis, and R/Sr in V1 showed highest predictions for PVR > 2 Wood Units (WU). Conclusion: In this study, Pwa, Ra in aVR, right or indeterminate axis deviations, and R/Sr in V1 and V2 showed statistically significant correlations with pulmonary hemodynamics, and Ra in aVR, R/Sr in V2 and V1, QRS axis, and Pwa contributed to variance for PASP, PAMP, and PVR, respectively. Moreover, Pwa, Ra in aVR, QRS axis, and R/Sr in V1 seem to provide relevant predictions for PH and precapillary PH.
dc.identifier.citationTokgöz, H. C., Öcal, B. E., Erkuş, Y. C., Tanyeri Üzel, S., Kültürsay, B., Tosun, A. ... Kaymaz, C. (2023). Remembering the Occam’s Razor: Could simple electrocardiographic findings provide relevant predictions for current hemodynamic criteria of pulmonary hypertension? Anatolian Journal of Cardiology, 27(11), 664-672. https://dx.doi.org/10.14744/AnatolJCardiol.2023.3181
dc.identifier.doi10.14744/AnatolJCardiol.2023.3181
dc.identifier.endpage672
dc.identifier.issn2149-2263
dc.identifier.issn2149-2271
dc.identifier.issue11
dc.identifier.pmid37842758
dc.identifier.scopus2-s2.0-85176265862
dc.identifier.scopusqualityQ3
dc.identifier.startpage664
dc.identifier.urihttps://dx.doi.org/10.14744/AnatolJCardiol.2023.3181
dc.identifier.urihttps://hdl.handle.net/20.500.12511/11876
dc.identifier.volume27
dc.identifier.wos001138681200010en_US
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorHakgör, Aykun
dc.language.isoen
dc.publisherTurkish Society of Cardiology
dc.relation.ispartofAnatolian Journal of Cardiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsAttribution-NonCommercial 4.0 International*
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttps://creativecommons.org/licenses/by-nc/4.0/*
dc.subjectElectrocardiogram
dc.subjectQRS Axis
dc.subjectPulmonary Hypertension
dc.titleRemembering the Occam’s Razor: Could simple electrocardiographic findings provide relevant predictions for current hemodynamic criteria of pulmonary hypertension?
dc.typeArticle

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