Medical ozone therapy for the inner ear acoustic trauma

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dc.contributor.authorYenigün, Alper
dc.contributor.authorAksoy, Fadlullah
dc.contributor.authorDoğan, Remzi
dc.contributor.authorYılmaz, Fahrettin
dc.contributor.authorVeyseller, Bayram
dc.contributor.authorÖzturan, Orhan
dc.contributor.authorÖztürk, Burak
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T19:56:48Z
dc.date.available10.07.201910:49:13
dc.date.available2019-07-10T19:56:48Z
dc.date.issued2013
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Kulak Burun Boğaz Hastalıkları Ana Bilim Dalı
dc.descriptionWOS: 000324363400025
dc.descriptionPubMed ID: 23871516
dc.description.abstractObjectives: The goal of the study was to look at the potential protective effect of ozone therapy by studying its antioxidant and vasodilatation effects against hearing loss caused by acoustic trauma. Methods: Thirty-two male Wistar Albino rats were divided into four groups of eight. The 1st group was exposed to acoustic trauma, the 2nd group was treated with ozone initially, and was exposed to acoustic trauma 24 h later, the 3rd group received ozone without trauma, while the 4th group was the control group. The 1st and 2nd groups were exposed to acoustic trauma with 105 dB SPL white band noise for 4 h. DPOAE and ABR tests were conducted in all groups on the 1st, 5th, and 10th days after trauma. Results: In the 1st group, the effects of acoustic trauma continued on days 1, 5 and 10. The 2nd group's DPOAE and ABR results on days 5 and 10 showed significant improvement at all frequencies compared to deterioration on day 1, and the readings were comparable to baseline measurements. Conclusion: Acoustic trauma is a pathology that is experienced frequently and leads to many problems in terms of health and cost. Ozone was demonstrated to be a reparative substance against acoustic trauma and, in addition, it can be supplied and applied easily.
dc.identifier.citationYenigün, A., Aksoy, F., Doğan, R., Yılmaz, F., Veyseller, B., Özturan, O. ve Öztürk, B. (2013). Medical ozone therapy for the inner ear acoustic trauma. International Journal Of Pediatric Otorhinolaryngology, 77(9), 1512-1517. https://dx.doi.org/10.1016/j.ijporl.2013.06.020
dc.identifier.doi10.1016/j.ijporl.2013.06.020
dc.identifier.endpage1517
dc.identifier.issn0165-5876
dc.identifier.issn1872-8464
dc.identifier.issue9
dc.identifier.scopusqualityQ1
dc.identifier.startpage1512
dc.identifier.urihttps://dx.doi.org/10.1016/j.ijporl.2013.06.020
dc.identifier.urihttps://hdl.handle.net/20.500.12511/2821
dc.identifier.volume77
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherElsevier Ireland Ltd
dc.relation.ispartofInternational Journal Of Pediatric Otorhinolaryngologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectAcoustic Trauma
dc.subjectOzone Therapy
dc.subjectInner Ear
dc.subjectOtoacoustic Emission
dc.subjectAuditory Brainstem Response
dc.titleMedical ozone therapy for the inner ear acoustic trauma
dc.typeArticle

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