A comparison of corneal biomechanical properties in patients with psoriasis and healthy subjects

dc.authorid0000-0001-9829-7268
dc.contributor.authorÇelik, Uğur
dc.contributor.authorAykut, Veysel
dc.contributor.authorÇelik, Burcu
dc.contributor.authorTaş, Mehmet
dc.contributor.authorYazgan, Serpil
dc.contributor.authorKaldırım, Havva
dc.contributor.authorKaraman Erdur, Sevil
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T19:56:00Z
dc.date.available10.07.201910:49:13
dc.date.available2019-07-10T19:56:00Z
dc.date.issued2015
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Göz Hastalıkları Ana Bilim Dalı
dc.descriptionWOS: 000350136600014
dc.descriptionPubMed ID: 25503911
dc.description.abstractObjective: To evaluate the differences in corneal biomechanical properties between healthy subjects and patients with psoriasis using the ocular response analyzer (ORA). Methods: Fifty-nine eyes of 59 psoriasis patients and 66 healthy individuals were included in the study. Corneal biomechanical parameters were obtained using ORA. Ultrasound pachymetry was used to measure central corneal thickness (CCT). The main parameters assessed were corneal hysteresis (CH), corneal resistance factor (CRF), Goldmann-correlated intraocular pressure (IOPg) measurement and corneal-compensated IOP (IOPcc) through ORA. The dry eye evaluation was performed with tear break-up time (TBUT) and Shirmer test. Results: The mean CH values in psoriasis and healthy subject eyes were 10.75 +/- 2.9 mm Hg, 11.97 +/- 3.6 mm Hg, respectively (P=0.047). The mean CRF values were 10.14 +/- 3.1 mm Hg and 11.61 +/- 3.3 mm Hg, respectively (P=0.012). The mean CCT were 539.1 +/- 36 mu m and 536.3 +/- 28 mu m, respectively (P=0.643). Mean TBUT values were 8.2 +/- 2.9 sec in psoriasis group and 10.4 +/- 3.6 sec in healthy subjects (P<0.001). Shirmer test values were less (8.9 +/- 3.8 mm/5 min) in psoriasis than in healthy subjects (13.1 +/- 3.6 mm) (P<0.001). Conclusions: Psoriasis can influence the corneal biomechanical properties. Patients with psoriasis had lower CH and CRF, but higher IOPg and IOPcc values than healthy controls. These corneal biomechanical changes should be considered when determining IOP values.
dc.identifier.citationÇelik, U., Aykut, V., Çelik, B., Taş, M., Yazgan, S., Kaldırım, H. ... Karaman Erdur, S. (2015). A comparison of corneal biomechanical properties in patients with psoriasis and healthy subjects. Eye & Constact Lens-Science And Clinical Practice, 41(2), 127-129. https://dx.doi.org/10.1097/ICL.0000000000000086
dc.identifier.doi10.1097/ICL.0000000000000086
dc.identifier.endpage129
dc.identifier.issn1542-2321
dc.identifier.issn1542-233X
dc.identifier.issue2
dc.identifier.scopusqualityQ2
dc.identifier.startpage127
dc.identifier.urihttps://dx.doi.org/10.1097/ICL.0000000000000086
dc.identifier.urihttps://hdl.handle.net/20.500.12511/2521
dc.identifier.volume41
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherLippincott Williams & Wilkins
dc.relation.ispartofEye & Constact Lens-Science and Clinical Practiceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/embargoedAccess
dc.subjectCorneal Biomechanical Properties
dc.subjectOcular Surface
dc.subjectPsoriasis
dc.titleA comparison of corneal biomechanical properties in patients with psoriasis and healthy subjects
dc.typeArticle

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