Platelet-rich plasma injection is more effective than hyaluronic acid in the treatment of knee osteoarthritis

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dc.authorid0000-0002-4843-5121
dc.contributor.authorSay, Ferhat
dc.contributor.authorGüler, Deniz
dc.contributor.authorYener, Kamil
dc.contributor.authorBülbül, Murat
dc.contributor.authorMalkoç, Melih
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T19:35:22Z
dc.date.available10.07.201910:49:14
dc.date.available2019-07-10T19:35:22Z
dc.date.issued2013
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Ortopedi ve Travmatoloji Ana Bilim Dalı
dc.description.abstractPURPOSE OF THE STUDY: There is increasing use of platelet-rich plasma (PRP) in orthopaedics as it is a simple, cheap and minimally invasive technique. This study aimed to compare the effects of the use of PRP and hyaluronic acid (HA) injections in the knee of patients diagnosed with and being followed-up for degenerative arthritis. MATERIALS AND METHODS: This prospective study included 90 patients with complaints of knee pain with findings of mild or moderate degenerative arthritis. In the PRP group (n = 45), one intra-articular injection was applied and in the HA group (n = 45), three doses of intra-articular injection were applied. Clinical evaluation was made by Knee Injury and Osteoarthritis Outcome Score (KOOS) and avisual pain scale. RESULTS: No severe adverse events was observed. Statistically significant better results in the KOOS score and visual pain scale was determined in PRP group than HA group at 3 months and 6 months follow up. The cost of the application for the PRP group was lower than that of the HA group. CONCLUSION The results of this study have shown the application of single dose PRP to be a safe, effective and low-cost method for treating OA. However, further studies are required for amore clear result.
dc.identifier.citationSay, F., Güler, D., Yener, K., Bülbül, M. ve Malkoç, M. (2013). Platelet-rich plasma injection is more effective than hyaluronic acid in the treatment of knee osteoarthritis. Acta Chirurgiae Orthopaedicae et Traumatologiae Cechoslovaca, 80(4), 278-283.
dc.identifier.endpage283
dc.identifier.issn0001-5415
dc.identifier.issue4
dc.identifier.scopusqualityQ3
dc.identifier.startpage278
dc.identifier.urihttps://hdl.handle.net/20.500.12511/738
dc.identifier.volume80
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherGalen S.R.O.
dc.relation.ispartofActa Chirurgiae Orthopaedicae et Traumatologiae Cechoslovacaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectGrowth Factors
dc.subjectHyaluronic Acid
dc.subjectKnee Osteoarthritis
dc.subjectPlatelet-Rich Plasma
dc.titlePlatelet-rich plasma injection is more effective than hyaluronic acid in the treatment of knee osteoarthritis
dc.title.alternativeInjekce plazmy obohacené desti?kov?m koncentrátem je efektivn?jší ne? kyselina hyaluronová v lé?b? gonartrózy
dc.typeArticle

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