Assessment of the clinical course of human rhinovirus/enterovirus infections in pediatric intensive care

Basit Öğe Kaydı
dc.authorid0000-0003-0037-7636
dc.authorid0000-0003-0042-0569
dc.contributor.authorKoçoğlu Barlas, Ülkem
dc.contributor.authorAkçay, Nihal
dc.contributor.authorMenentoğlu, Mehmet Emin
dc.contributor.authorŞevketoğlu, Esra
dc.contributor.authorDuyu, Muhterem
dc.contributor.authorTelhan, Leyla
dc.contributor.authorKanğın, Murat
dc.contributor.authorTuğrul, Hazal Ceren
dc.contributor.authorErdoğan, Seher
dc.contributor.authorDurak, Cansu
dc.contributor.authorGüney Şahin, Ebru
dc.contributor.authorUmur, Özge
dc.contributor.authorŞık, Sare Güntülü
dc.date.accessioned2023-12-18T10:57:27Z
dc.date.available2023-12-18T10:57:27Z
dc.date.issued2023
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Çocuk Sağlığı ve Hastalıkları Ana Bilim Dalı
dc.description.abstractBackground: This study aims to evaluate the clinical course of human rhinovirus/enterovirus (HRV/EV) infections in the pediatric intensive care unit. Methods: The study was conducted as a multicenter, prospective observational study from September 2022 to December 2022. Cases with positive polymerase chain reaction testing for HRV/EV of nasopharyngeal swab samples within the first 24 hours of pediatric intensive care unit admission were recorded. There were 2 groups: 1-24 months and >24 months. Results: A total of 75 cases (39 male) were included in the study. The median age for all cases was 21 months. The highest polymerase chain reaction positivity rates were observed in October (37.33%). Among the cases, 32 (42.67%) presented with bronchopneumonia/pneumonia, 24 (32%) presented with acute bronchiolitis/bronchitis and 7 (9.33%) presented with sepsis/septic shock. The frequency of pediatric acute respiratory distress syndrome was found to be 6.67%. In the age group of 1-24 months, mean lymphocyte and liver enzyme levels were higher, while in the age group of >24 months, mean hemoglobin and mean kidney function test levels were higher (P ? 0.05). Continuous oxygen therapy was provided to 65.3% of the cases, noninvasive ventilation to 33.3%, high-flow nasal cannula-oxygen therapy to 32% and invasive mechanical ventilation to 16%. Conclusions: HRV/EV infections primarily affect the respiratory system and generally exhibit a clinical course with low mortality rates (1, 1.3%). In cases with underlying chronic diseases, more severe clinical conditions such as pediatric acute respiratory distress syndrome and septic shock may occur.
dc.identifier.citationKoçoğlu Barlas, Ü., Akçay, N., Menentoğlu, M. E., Şevketoğlu, E., Duyu, M., Telhan, L. ... Şık, S. G. (2023). Assessment of the clinical course of human rhinovirus/enterovirus infections in pediatric intensive care. Pediatric Infectious Disease Journal, 42(12), E454-E460. https://dx.doi.org/10.1097/INF.0000000000004127
dc.identifier.doi10.1097/INF.0000000000004127
dc.identifier.endpageE460
dc.identifier.issn0891-3668
dc.identifier.issn1532-0987
dc.identifier.issue12
dc.identifier.pmid37820286
dc.identifier.scopus2-s2.0-85178495862
dc.identifier.scopusqualityQ1
dc.identifier.startpageE454
dc.identifier.urihttps://dx.doi.org/10.1097/INF.0000000000004127
dc.identifier.urihttps://hdl.handle.net/20.500.12511/12021
dc.identifier.volume42
dc.identifier.wos001107102900028en_US
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorTelhan, Leyla
dc.institutionauthorKanğın, Murat
dc.language.isoen
dc.publisherLippincott Williams and Wilkins
dc.relation.ispartofPediatric Infectious Disease Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/embargoedAccess
dc.subjectEnterovirus
dc.subjectIntensive Care
dc.subjectPediatric
dc.subjectRhinovirus
dc.subjectVentilation
dc.titleAssessment of the clinical course of human rhinovirus/enterovirus infections in pediatric intensive care
dc.typeArticle

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim Yok
İsim:
Telhan-Leyla-2023.pdf
Boyut:
426.22 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin / Full Text
İndir
Lisans paketi
Listeleniyor 1 - 1 / 1
Küçük Resim Yok
İsim:
license.txt
Boyut:
1.44 KB
Biçim:
Item-specific license agreed upon to submission
Açıklama:
İndir

Koleksiyon

Makale Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu