Role of multiparametric prostate MRI in the management of prostate cancer

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dc.authorid0000-0001-8014-2321
dc.contributor.authorO'Connor, Luke P.
dc.contributor.authorLebastchi, Amir H.
dc.contributor.authorHoruz, Rahim
dc.contributor.authorRastinehad, Ardeshir R.
dc.contributor.authorSiddiqui, M. Minhaj
dc.contributor.authorGrummet, Jeremy
dc.contributor.authorKastner, Christof
dc.contributor.authorAhmed, Hashim U.
dc.contributor.authorPinto, Peter A.
dc.contributor.authorTürkbey, Barış
dc.date.accessioned2021-04-07T10:25:08Z
dc.date.available2021-04-07T10:25:08Z
dc.date.issued2021
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Üroloji Ana Bilim Dalı
dc.description.abstractIntroduction Prostate cancer has traditionally been diagnosed by an elevation in PSA or abnormal exam leading to a systematic transrectal ultrasound (TRUS)-guided biopsy. This diagnostic pathway underdiagnoses clinically significant disease while over diagnosing clinically insignificant disease. In this review, we aim to provide an overview of the recent literature regarding the role of multiparametric MRI (mpMRI) in the management of prostate cancer. Materials and Methods A thorough literature review was performed using PubMed to identify articles discussing use of mpMRI of the prostate in management of prostate cancer. Conclusion The incorporation of mpMRI of the prostate addresses the shortcomings of the prostate biopsy while providing several other advantages. mpMRI allows some men to avoid an immediate biopsy and permits visualization of areas likely to harbor clinically significant cancer prior to biopsy to facilitate use of MR-targeted prostate biopsies. This allows for reduction in diagnosis of clinically insignificant disease as well as improved detection and better characterization of higher risk cancers, as well as the improved selection of patients for active surveillance. In addition, mpMRI can be used for selection and monitoring of patients for active surveillance and treatment planning during surgery and focal therapy.
dc.description.sponsorshipUnited States Department of Health & Human Services National Institutes of Health (NIH) - USA ; Doris Duke Charitable Foundation (DDCF) ; American Association for Dental Research ; Colgate-Palmolive Company ; Roche Holding ; Genentechen_US
dc.identifier.citationO'Connor, L. P., Lebastchi, A. H., Horuz, R., Rastinehad, A. R., Siddiqui, M. M., Grummet, J. ... Türkbey, B. (2021). Role of multiparametric prostate MRI in the management of prostate cancer. World Journal of Urology, 39(3), 651-659. https://dx.doi.org/10.1007/s00345-020-03310-z
dc.identifier.doi10.1007/s00345-020-03310-z
dc.identifier.endpage659
dc.identifier.issn0724-4983
dc.identifier.issn1433-8726
dc.identifier.issue3
dc.identifier.scopusqualityQ1
dc.identifier.startpage651
dc.identifier.urihttps://dx.doi.org/10.1007/s00345-020-03310-z
dc.identifier.urihttps://hdl.handle.net/20.500.12511/6712
dc.identifier.volume39
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherSpringer
dc.relation.ispartofWorld Journal of Urologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/embargoedAccess
dc.subjectProstate Cancer
dc.subjectMultiparametric MRI (mpMRI)
dc.subjectFusion Biopsy
dc.subjectActive Surveillance
dc.subjectProstatectomy
dc.titleRole of multiparametric prostate MRI in the management of prostate cancer
dc.typeArticle

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