Paracervical block before laparoscopic total hysterectomy: a randomized controlled trial

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dc.contributor.authorGüngördük, Kemal
dc.contributor.authorGülseren, Varol
dc.contributor.authorTaştan, Leyla
dc.contributor.authorÖzdemir, İsa Aykut
dc.date.accessioned2025-10-11T13:16:50Z
dc.date.available2025-10-11T13:16:50Z
dc.date.issued2024
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Kadın Hastalıkları ve Doğum Ana Bilim Dalı
dc.description.abstractObjective: To test the hypothesis that paracervical block with 0.5 % bupivacaine decreases postoperative pain after total laparoscopic hysterectomy (TLH). Materials and method: This randomized double-blind placebo control trial included 152 women. We injected 10 mL 0.5 % bupivacaine (study group, n = 75) or 10 mL normal saline (control group, n = 77) at the 3 and 9 o'clock positions of the uterine cervix. The primary outcome was the visual analog scale score (VAS) determined 1 h (h) postoperatively. Results: The 152 patients did not differ in their baseline demographics or perioperative characteristics. The mean VAS 1 h postoperatively was significantly lower in the study group than in controls (5.7 ± 1.2 vs. 6.8 ± 1.1, P < 0.001). The average VAS at 30 min, 3 h, and 6 h postoperatively was also significantly lower in the study group. Patients in the study group had a significantly lower analgesic requirement than did controls during the first 24 h postoperatively (6 [7.8 %] vs. 16 [21 %], P = 0.021). Total QoR-40 questionnaire scores were higher in patients who received bupivacaine. Conclusion: Paracervical bloc with 0.5 % bupivacaine just before TLH is an effective and safe method to reduce pain and lower postoperative analgesic requirement. URL link that leads directly to the trial registration: https://clinicaltrials.gov/ct2/show/NCT05341869?cond=NCT05341869&draw=2&rank=1.
dc.identifier.citationGüngördük, K., Gülseren, V., Taştan, L. ve Özdemir, İ. A. (2024). Paracervical block before laparoscopic total hysterectomy: a randomized controlled trial. Taiwanese Journal of Obstetrics and Gynecology, 63(2), 186-191. http://dx.doi.org/10.1016/j.tjog.2024.01.013
dc.identifier.doi10.1016/j.tjog.2024.01.013
dc.identifier.endpage191
dc.identifier.issn1028-4559
dc.identifier.issue2
dc.identifier.pmid38485313
dc.identifier.scopus2-s2.0-85184034788
dc.identifier.scopusqualityQ3
dc.identifier.startpage186
dc.identifier.urihttp://dx.doi.org/10.1016/j.tjog.2024.01.013
dc.identifier.urihttps://hdl.handle.net/20.500.12511/13085
dc.identifier.volume63
dc.identifier.wosWOS:001300736700001
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorÖzdemir, İsa Aykut
dc.language.isoen
dc.relation.ispartofTaiwanese Journal of Obstetrics and Gynecology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectLaparoscopic Hysterectomy
dc.subjectParacervical Block
dc.subjectRandomized Trial
dc.titleParacervical block before laparoscopic total hysterectomy: a randomized controlled trial
dc.typeArticle

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