Could the long-term oncological safety of laparoscopic surgery in low-risk endometrial cancer also be valid for the high–intermediate-and high-risk patients? A multi-center turkish gynecologic oncology group study conducted with 2745 endometrial cancer cases. (TRSGO-End-001)

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dc.contributor.authorVardar, Mehmet Ali
dc.contributor.authorGüzel, Ahmet Barış
dc.contributor.authorTaşkın, Selen
dc.contributor.authorGüngör, Mete
dc.contributor.authorÖzgül, Nejat
dc.contributor.authorSalman, Coşkun
dc.contributor.authorKüçükgöz Güleç, Ümran
dc.contributor.authorKhatib, Ghada
dc.contributor.authorTaşkıran, Çağatay
dc.contributor.authorDünder, İlkkan
dc.contributor.authorOrtaç, Fırat
dc.contributor.authorYüce, Kunter
dc.contributor.authorTerek, Coşan
dc.contributor.authorŞimşek, Tayup
dc.contributor.authorÖzsaran, Aydın
dc.contributor.authorOnan, Anıl
dc.contributor.authorÇoban, Gonca
dc.contributor.authorTopuz, Samet
dc.contributor.authorDemirkıran, Fuat
dc.contributor.authorTakmaz, Özgüç
dc.contributor.authorKöse, Mehmet Faruk
dc.contributor.authorGöçmen, Ahmet
dc.contributor.authorSeydaoğlu, Gülşah
dc.contributor.authorGümürdülü, Derya
dc.contributor.authorAyhan, Ali
dc.date.accessioned2021-11-30T09:51:05Z
dc.date.available2021-11-30T09:51:05Z
dc.date.issued2021
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Kadın Hastalıkları ve Doğum Ana Bilim Dalı
dc.description.abstractThis study was conducted to compare the long-term oncological outcomes of laparotomy and laparoscopic surgeries in endometrial cancer under the light of the 2016 ESMO-ESGO-ESTRO risk classification system, with particular focus on the high–intermediate-and high-risk categories. Using multicentric databases between January 2005 and January 2016, disease-free and overall survivals of 2745 endometrial cancer cases were compared according to the surgery route (laparotomy vs. laparoscopy). The high–intermediate-and high-risk patients were defined with respect to the 2016 ESMO-ESGO-ESTRO risk classification system, and they were analyzed with respect to differences in survival rates. Of the 2745 patients, 1743 (63.5%) were operated by laparotomy, and the remaining were operated with laparoscopy. The total numbers of high–intermediate- and high-risk endometrial cancer cases were 734 (45%) patients in the laparotomy group and 307 (30.7%) patients in the laparoscopy group. Disease-free and overall survivals were not statistically different when compared between laparoscopy and laparotomy groups in terms of low-, intermediate-, high–intermediateand high-risk endometrial cancer. In conclusion, regardless of the endometrial cancer risk category, long-term oncological outcomes of the laparoscopic approach were found to be comparable to those treated with laparotomy. Our results are encouraging to consider laparoscopic surgery for high–intermediate- and high-risk endometrial cancer cases.
dc.identifier.citationVardar, M. A., Güzel, A. B., Taşkın, S., Güngör, M., Özgül, N., Salman, C. ... Ayhan, A. (2021). Could the long-term oncological safety of laparoscopic surgery in low-risk endometrial cancer also be valid for the high–intermediate-and high-risk patients? A multi-center turkish gynecologic oncology group study conducted with 2745 endometrial cancer cases. (TRSGO-End-001). Current Oncology, 28(6), 4328-4340. https://dx.doi.org/10.3390/curroncol28060368
dc.identifier.doi10.3390/curroncol28060368
dc.identifier.endpage4340
dc.identifier.issn1718-7729
dc.identifier.issn1198-0052
dc.identifier.issue6
dc.identifier.scopusqualityQ2
dc.identifier.startpage4328
dc.identifier.urihttps://dx.doi.org/10.3390/curroncol28060368
dc.identifier.urihttps://hdl.handle.net/20.500.12511/8593
dc.identifier.volume28
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherMDPI
dc.relation.ispartofCurrent Oncologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsAttribution 4.0 International*
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/*
dc.subjectHigh-Risk Endometrial Cancer
dc.subjectLaparoscopic Surgery
dc.subjectSurvival
dc.titleCould the long-term oncological safety of laparoscopic surgery in low-risk endometrial cancer also be valid for the high–intermediate-and high-risk patients? A multi-center turkish gynecologic oncology group study conducted with 2745 endometrial cancer cases. (TRSGO-End-001)
dc.typeArticle

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