Predictive value of different glycemic control markers in total hip or knee arthroplasty: A prospective study

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dc.authorid0000-0003-0926-3029
dc.authorid0000-0002-6268-9910
dc.contributor.authorÇetik, Rıza Mert
dc.contributor.authorAzboy, İbrahim
dc.contributor.authorBirinci, Murat
dc.contributor.authorÖztürkmen, Yusuf
dc.contributor.authorKalyenci, Ahmet Sinan
dc.contributor.authorAtilla, Bülent
dc.date.accessioned2023-11-14T06:46:06Z
dc.date.available2023-11-14T06:46:06Z
dc.date.issued2023
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Ortopedi ve Travmatoloji Ana Bilim Dalı
dc.description.abstractObjective: The optimal glycemic control marker before total hip or knee arthroplasty remains inconclusive. Hemoglobin A1c (HbA1c) is widely used, while fructosamine may be valuable for predicting periprosthetic joint infection (PJI). Fructosamine levels can be affected by serum albumin levels; albumin-corrected fructosamine (AlbF) can be calculated to overcome this issue. The objective of this study was to evaluate the predictive value of different markers for complications after primary total hip or knee arthroplasty. Methods: This prospective cohort study included 304 patients (mean age: 65 years [range, 16-85), mean follow-up: 32 months (range, 12-49)] who underwent primary total hip or knee arthroplasty between 2018 and 2021. Of them, 156 patients had diabetes. Mean HbA1c was 6.5% (range, 4.8%-13%), fructosamine 244 µmol/L (range, 98-566 µmol/L), and AlbF 632 (range, 238-2308). Patients who did and did not have diabetes were matched 1: 1. Hemoglobin A1c 7% and fructosamine 292 µmol/L were used as cutoff. Complications were documented. Glycemic markers were compared using logistic regression analyses, with a special focus on PJI. Results: In the logistic regression analyses, HbA1c was strongly associated with total complications [adjusted odds ratio (OR): 3.61; 95% CI, 1.65-7.91, P = .001], while fructosamine was associated with PJI (adjusted OR: 13.68; 95% CI, 1.39-134.89, P = .025). Albumin-corrected fructosamine did not show any additional benefits. Conclusion: Preoperative assessment before total hip or knee arthroplasty must not focus on a single marker; HbA1c is a good predictor of total complications, while fructosamine is a better predictor of PJI. To the best of our knowledge, in its first orthopedic study, AlbF did not show any advantages. Level of Evidence: Level II, Prognostic Study.
dc.identifier.citationÇetik, R. M., Azboy, İ., Birinci, M., Öztürkmen, Y., Kalyenci, A. S. ve Atilla, B. (2023). Predictive value of different glycemic control markers in total hip or knee arthroplasty: A prospective study. Acta Orthopaedica et Traumatologica Turcica, 57(5), 289-293. https://dx.doi.org/10.5152/j.aott.2023.23037
dc.identifier.doi10.5152/j.aott.2023.23037
dc.identifier.endpage293
dc.identifier.issn1017-995X
dc.identifier.issn2589-1294
dc.identifier.issue5
dc.identifier.pmid37823741
dc.identifier.scopus2-s2.0-85175351937
dc.identifier.scopusqualityQ2
dc.identifier.startpage289
dc.identifier.urihttps://dx.doi.org/10.5152/j.aott.2023.23037
dc.identifier.urihttps://hdl.handle.net/20.500.12511/11770
dc.identifier.volume57
dc.identifier.wos001127628500004en_US
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorAzboy, İbrahim
dc.institutionauthorBirinci, Murat
dc.language.isoen
dc.publisherAVES
dc.relation.ispartofActa Orthopaedica et Traumatologica Turcicaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsAttribution-NonCommercial 4.0 International*
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttps://creativecommons.org/licenses/by-nc/4.0/*
dc.subjectArthroplasty
dc.subjectDiabetes Mellitus
dc.subjectHip Arthroplasty
dc.subjectInfection
dc.subjectKnee Arthroplasty
dc.titlePredictive value of different glycemic control markers in total hip or knee arthroplasty: A prospective study
dc.typeArticle

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