The association of left atrial mechanics with left ventricular morphology in patients with hypertrophic cardiomyopathy: A cardiac magnetic resonance study

dc.authorid0000-0002-4607-5724
dc.contributor.authorGüler, Arda
dc.contributor.authorTopel, Çağdaş
dc.contributor.authorŞahin, Ahmet Anıl
dc.contributor.authorAydın, Sinem
dc.contributor.authorGüler, Ekrem
dc.contributor.authorMemiç Sancar, Kadriye
dc.contributor.authorTürkvatan Cansever, Aysel
dc.contributor.authorGüler, Gamze Babur
dc.contributor.authorErtürk, Mehmet
dc.date.accessioned2023-03-17T07:28:44Z
dc.date.available2023-03-17T07:28:44Z
dc.date.issued2023
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Kardiyoloji Ana Bilim Dalı
dc.description.abstractPurpose: Hypertrophic cardiomyopathy (HCM) is related with structural and pathologic changes in the left atrium (LA) and left ventricle (LV). The aim of this study was to explore the association between LA mechanics and LV charac-teristics in patients with HCM using cardiac magnetic resonance feature tracking (CMR-FT). Material and methods: A total of 76 patients with HCM and 26 healthy controls were included in the study. The pa-rameters including the extent of LV late gadolinium enhancement (LGE-%) and the LV early diastolic longitudinal strain rate (edLSR) were assessed for LV. LA conduit, booster, and reservoir functions were assessed by LA fractional volumes and strain analyses using CMR-FT. HCM patients were classified as HCM patients without LGE, with mild LGE-% (0% < LGE-% >= 10%), and prominent LGE-% (10% < LGE-%).Results: HCM patients had worse LA functions compared with the controls (p < 0.05). The majority of LA functional indices were more impaired in HCM patients with regard to LGE. LA volumes were higher in HCM patients with prominent LGE-% compared with HCM patients with mild LGE-% (p < 0.05). However, only a minority of LA functional parameters differed between the 2 groups. LA strain parameters showed weak to modest correlations with LV LGE-% and LV edLSR.Conclusions: LV characteristics, to some extent, influence LA mechanics, but they might not be the only factor induc-ing LA dysfunction in patients with HCM.
dc.identifier.citationGüler, A., Topel, Ç., Şahin, A. A., Aydın, S., Güler, E., Memiç Sancar, K. ... Ertürk, M. (2023). The association of left atrial mechanics with left ventricular morphology in patients with hypertrophic cardiomyopathy: A cardiac magnetic resonance study. Polish Journal of Radiology, 88, e103-e112. https://dx.doi.org/10.5114/pjr.2023.125213
dc.identifier.doi10.5114/pjr.2023.125213
dc.identifier.endpagee112
dc.identifier.issn0137-7183
dc.identifier.issn1899-0967
dc.identifier.pmid36910882
dc.identifier.scopus2-s2.0-85149405781
dc.identifier.scopusqualityQ3
dc.identifier.startpagee103
dc.identifier.urihttps://dx.doi.org/10.5114/pjr.2023.125213
dc.identifier.urihttps://hdl.handle.net/20.500.12511/10629
dc.identifier.volume88
dc.identifier.wos000938453200001en_US
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorGüler, Ekrem
dc.language.isoen
dc.publisherInternational Scientific Information, Inc.
dc.relation.ispartofPolish Journal of Radiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International*
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectCardiac Magnetic Resonance
dc.subjectHypertrophic Cardiomyopathy
dc.subjectLeft Atrium
dc.subjectLate Gadolinium Enhancement
dc.titleThe association of left atrial mechanics with left ventricular morphology in patients with hypertrophic cardiomyopathy: A cardiac magnetic resonance study
dc.typeArticle

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