Addition of the duration of ST segment depression to Duke treadmill score for diagnostic accuracy of exercise electrocardiography to predict obstructive coronary artery disease

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dc.authorid0000-0003-0205-1138
dc.authorid0000-0001-6643-9364
dc.contributor.authorTurhan Çağlar, Fatma Nihan
dc.contributor.authorGök, Gülay
dc.contributor.authorÖztimer, Gülsüm
dc.contributor.authorKatkat, Fahrettin
dc.contributor.authorKarakozak, Dilay
dc.contributor.authorÖztaş, Didem Melis
dc.contributor.authorBeyaz, Metin Onur
dc.contributor.authorUğurlucan, Murat
dc.date.accessioned2022-12-15T12:04:26Z
dc.date.available2022-12-15T12:04:26Z
dc.date.issued2022
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Kardiyoloji Ana Bilim Dalı
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Kalp ve Damar Cerrahisi Ana Bilim Dalı
dc.description.abstractIntroduction Exercise electrocardiography (EET) is a safe and cost-effective method to predict the presence, prognosis, and severity of coronary artery disease (CAD). Various score models have been developed to increase predictive power of EET. In this study, we aimed to evaluate whether adding ST depression duration could have an effect on increasing the value of Duke treadmill score (DTS) in predicting obstructive CAD. Methods In this single centred, cross-sectional study, we evaluated a total of 258 patients who presented with a complaint of chest pain and undergone coronary angiogram in result of a positive EET. DTS was calculated for all the patients. The new score-revised DTS- was calculated by adding total ST depression time to classical DS parameters. We compared area under the curve (AUC) of DTS and revised DTS by Delongi method. Results Mean age of the group was 58.43 +/- 9.37, and 37.2% (n = 96) were female. Mean total ST-depression duration was 171.72 +/- 91.43 msec in normal artery group,241.54 +/- 118.11 msec in non-obstructive CAD group, and 281.26 +/- 113.64 in obstructive CAD group.ST-depression duration in both exercise and recovery, and total ST depression duration were significantly higher in obstructive CAD group than non-obstructive and normal artery groups (p = 0.024, p = 0.01, p < 0.01, and p < 0.01, respectively). Revised DTS had significantly higher predictive value of obstructive CAD compared to classical DS (AUC (95%CI): 0.744 vs. 0.626, p < 0.001). The AUC of DS was significantly lower than the new score (z-score:3.274, p = 0.011). Conclusion In conclusion, adding ST depression duration to DTS calculation is increasing the discriminative value of DTS to predict obstructive CAD. Benefits of EET within the context of the management of CAD is well-known, hence, it is clear that physicians may use revised DTS.
dc.identifier.citationTurhan Çağlar, F. N., Gök, G., Öztimer, G., Katkat, F., Karakozak, D., Öztaş, D. M. ... Uğurlucan, M. (2022). Addition of the duration of ST segment depression to Duke treadmill score for diagnostic accuracy of exercise electrocardiography to predict obstructive coronary artery disease. Acta Cardiologica, 77(6), 494-500. https://doi.org/10.1080/00015385.2021.1964210
dc.identifier.doi10.1080/00015385.2021.1964210
dc.identifier.endpage500
dc.identifier.issn0001-5385
dc.identifier.issn1784-973X
dc.identifier.issue6
dc.identifier.pmid34412552
dc.identifier.scopus2-s2.0-85113808641
dc.identifier.scopusqualityQ3
dc.identifier.startpage494
dc.identifier.urihttps://doi.org/10.1080/00015385.2021.1964210
dc.identifier.urihttps://hdl.handle.net/20.500.12511/10130
dc.identifier.volume77
dc.identifier.wos000686856300001en_US
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorGök, Gülay
dc.institutionauthorUğurlucan, Murat
dc.language.isoen
dc.publisherTaylor & Francis Ltd
dc.relation.ispartofActa Cardiologicaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/embargoedAccess
dc.subjectCoronary Artery Disease
dc.subjectDuke Score
dc.subjectExercise Electrocardiography
dc.titleAddition of the duration of ST segment depression to Duke treadmill score for diagnostic accuracy of exercise electrocardiography to predict obstructive coronary artery disease
dc.typeArticle

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