A candidate single nucleotide polymorphism in the 3' untranslated region (rs17878624) of survivin gene for NSCLC

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dc.contributor.authorAynacı, Engin
dc.contributor.authorCoşkunpınar, Ender
dc.contributor.authorYıldız, Pınar
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T19:51:04Z
dc.date.available10.07.201910:49:13
dc.date.available2019-07-10T19:51:04Z
dc.date.issued2018
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Göğüs Hastalıkları Ana Bilim Dalı
dc.descriptionWOS: 000429488200020
dc.descriptionPubMed ID: 29631694
dc.description.abstractSurvivin is a gene that locates on human chromosome 17q25 and contains 142 amino acid. Survivin (BIRC5) is the first one of the found inhibitors of apoptosis proteins (IAPs) that is an important protein family and regulates apoptosis. It is expressed particularly in cancer cells. 3'UTR region of gene has components that is necessary for gene function and this region plays a critical role in the regulation of posttranscriptional regulation of the gene expression. Therefore, polymorphisms in this region may affect the function of the gene. The purpose of the study is to investigate possible relationship, that is associated with development and prognosis of the disease, between the 3'UTR region (rs17878624) polymorphism and NSCLC in a Turkish society.
dc.identifier.citationAynacı, E., Coşkunpınar, E. ve Yıldız, P. (2018). A candidate single nucleotide polymorphism in the 3' untranslated region (rs17878624) of survivin gene for NSCLC. Cellular and Molecular Biology, 64(4), 119-122. https://dx.doi.org/10.14715/cmb/2018.64.4.20
dc.identifier.doi10.14715/cmb/2018.64.4.20
dc.identifier.endpage122
dc.identifier.issn0145-5680
dc.identifier.issn1165-158X
dc.identifier.issue4
dc.identifier.scopusqualityQ3
dc.identifier.startpage119
dc.identifier.urihttps://dx.doi.org/10.14715/cmb/2018.64.4.20
dc.identifier.urihttps://hdl.handle.net/20.500.12511/2141
dc.identifier.volume64
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherC M B Assoc
dc.relation.ispartofCellular And Molecular Biologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectNSCLC
dc.subjectSurvivin
dc.subjectGene Polymorphism
dc.subject3'UTR
dc.titleA candidate single nucleotide polymorphism in the 3' untranslated region (rs17878624) of survivin gene for NSCLC
dc.typeArticle

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