Assessment of the role of serum 25-hydroxy vitamin D level on coronary heart disease risk with stratification among patients with type 2 diabetes mellitus

dc.authorid0000-0002-7902-5803
dc.authorid0000-0003-2209-7694
dc.contributor.authorBener, Abdulbari
dc.contributor.authorAl-Hamaq, Abdulla O. A. A.
dc.contributor.authorZughaier, Susu M.
dc.contributor.authorÖztürk, Mustafa
dc.contributor.authorÖmer, Abdulkadir
dc.date.accessioned2020-12-28T12:07:49Z
dc.date.available2020-12-28T12:07:49Z
dc.date.issued2021
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıkları Ana Bilim Dalı
dc.description.abstractWe investigated the role of vitamin D on glycemic regulation and cardiac complications in patients with type 2 diabetes mellitus (T2DM). A total of 1139 patients (49.3% males vs 50.7% females) were included. Information on sociodemographic lifestyle, family history, blood pressure (BP), and coronary heart disease (CHD) complications was collected. Significant differences were found between males and females regarding age-groups (P= .002), body mass index (BMI;P= .008), physical activity (P= .010), sheesha smoking (P= .016), cigarette smoking (P= .002), hypertension (P= .050), metabolic syndrome (P= .026), and CHD (P= .020). There were significant differences between vitamin D deficiency, insufficiency, and sufficiency in relation to age-group (P= .002), income (P= .002), waist circumference (P= .002), hip circumference (P= .028), waist-hip ratio (P= .002), and BMI (P= .002). Further, mean values of hemoglobin, magnesium, creatinine, hemoglobin A(1c)(HbA(1c)), total cholesterol, uric acid, and diastolic BP were significantly higher among patients with vitamin D deficiency compared with those with insufficiency and sufficiency. Multiple logistic regression analysis revealed that 25-hydroxy vitamin D, 25(OH)D, HbA(1c), waist circumference, uric acid, duration of T2DM, total cholesterol, systolic and diastolic BP, and BMI were strong predictor risk factors for CHD among patients with T2DM. The present study supports that 25(OH)D may have a direct effect on CHD and on its risk factors.
dc.description.sponsorshipQatar Diabetes Associationen_US
dc.description.sponsorshipIstanbul Medipol Universityen_US
dc.description.sponsorshipQatar Foundationen_US
dc.identifier.citationBener, A., Al-Hamaq, A. O. A. A., Zughaier, S. M., Öztürk, M. ve Ömer, A. (2021). Assessment of the role of serum 25-hydroxy vitamin D level on coronary heart disease risk with stratification among patients with type 2 diabetes mellitus. Angiology, 72(1), 86-92. https://dx.doi.org/10.1177/0003319720951411
dc.identifier.doi10.1177/0003319720951411
dc.identifier.endpage92
dc.identifier.issn0003-3197
dc.identifier.issn1940-1574
dc.identifier.issue1
dc.identifier.scopusqualityQ2
dc.identifier.startpage86
dc.identifier.urihttps://dx.doi.org/10.1177/0003319720951411
dc.identifier.urihttps://hdl.handle.net/20.500.12511/6154
dc.identifier.volume72
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherSAGE Publications Inc
dc.relation.ispartofAngiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/embargoedAccess
dc.subjectEpidemiology
dc.subjectDiabetes
dc.subjectComplications
dc.subjectCoronary Heart Disease
dc.subjectVitamin D
dc.titleAssessment of the role of serum 25-hydroxy vitamin D level on coronary heart disease risk with stratification among patients with type 2 diabetes mellitus
dc.typeArticle

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