Cholangiocarcinoma presenting with hypercalcemia and thrombocytopenia

Basit Öğe Kaydı
dc.authorid0000-0003-0428-2511
dc.contributor.authorBattal, Muharrem
dc.contributor.authorGürbulak, Bünyamin
dc.contributor.authorBostancı, Özgür
dc.contributor.authorYılmaz, Müveddet Banu
dc.contributor.authorÖzdenkaya, Yaşar
dc.contributor.authorKaratepe, O?uzhan
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T19:36:34Z
dc.date.available10.07.201910:49:14
dc.date.available2019-07-10T19:36:34Z
dc.date.issued2014
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Genel Cerrahi Ana Bilim Dalı
dc.description.abstractMalignant hypercalcemia and thrombocytopenia may result from bone metastasis of cholangiocarcinoma (CC). Our case was 53-year-old man admitted to emergency department with symptoms of anorexia, weight loss, nausea, vomiting, and general fatigue in February 2012. His laboratory findings showed hypercalcemia and thrombocytopenia. CT showed a large multinodular mass in the right lobe and, extending through left lobe of the liver. We considered the diagnosis of hypercalcemia of malignancy with elevated calcium levels and suppressed PTH level with the existence of skeletal bone metastasis and the absence of parathyroid gland pathology. Treatment of hypercalcemia with IV saline, furosemide, and calcitonin improved the patient symptoms. After the 8th day of admission, calcium level, thrombocytopenia, and other symptoms were normalized. Patient was sustained surgically inoperable and transferred to medical oncology department for the purpose of palliative chemotherapy and intended radiotherapy for bone metastasis. Hypercalcemia relapsed 4 weeks after discharge and patient died at the 5th month after admission due to disseminated metastasis. We should be aware of CC with symptomatic hypercalcemia and rarely low platelet count. The correction of hypercalcemia provides symptomatic relief and stability of patients.
dc.identifier.citationBattal, M., Gürbulak, B., Bostancı, Ö., Yılmaz, M. B., Özdenkaya, Y. ve Karatepe, O. (2014). Cholangiocarcinoma presenting with hypercalcemia and thrombocytopenia. Case Reports in Medicine, 2014. https://dx.doi.org/10.1155/2014/246817
dc.identifier.doi10.1155/2014/246817
dc.identifier.issn1687-9627
dc.identifier.scopusqualityN/A
dc.identifier.urihttps://hdl.handle.net/20.500.12511/1201
dc.identifier.urihttps://dx.doi.org/10.1155/2014/246817
dc.identifier.volume2014
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherHindawi Publishing Corporation
dc.relation.ispartofCase Reports in Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsAttribution 3.0 Unported*
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttps://creativecommons.org/licenses/by/3.0/*
dc.subjectHypercalcemia
dc.subjectThrombocytopenia
dc.subjectCholangiocarcinoma (CC)
dc.titleCholangiocarcinoma presenting with hypercalcemia and thrombocytopenia
dc.typeArticle

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
Ozdenkaya, Yasar-2014.pdf
Boyut:
768.06 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin / Full Text
İndir

Koleksiyon

Scopus İndeksli Yayınlar Koleksiyonu
Makale Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu