Aortic aneurysm evaluation by scanning acoustic microscopy and Raman spectroscopy

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dc.authorid0000-0001-9919-8392
dc.authorid0000-0001-6182-5055
dc.authorid0000-0001-6643-9364
dc.contributor.authorTanören, Bukem
dc.contributor.authorParlatan, Uğur
dc.contributor.authorParlak, Melita
dc.contributor.authorKeçoğlu, İbrahim
dc.contributor.authorBurçin Ünlü, Mehmet
dc.contributor.authorÖztaş, Didem Melis
dc.contributor.authorUlukan, Mustafa Özer
dc.contributor.authorErkanlı, Korhan
dc.contributor.authorUğurlucan, Murat
dc.date.accessioned2021-11-01T06:19:48Z
dc.date.available2021-11-01T06:19:48Z
dc.date.issued2021
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Kalp ve Damar Cerrahisi Ana Bilim Dalı
dc.description.abstractAortic aneurysm is observed as a result of the extensive alteration in the elasticity of the aortic wall due to the breakdown of elastin and collagen. In this study, we studied the feasibility of scanning acoustic microscopy (SAM) and Raman spectroscopy (RS) in characterizing the dilated segments of the aorta from male and female patients with aortic aneurysm. SAM determined the acoustic property variation in the aorta by calculating the acoustic impedance values of aorta samples of 18 patients. RS determined the disease states by analyzing the chemical variation especially in the peaks related to elastin and collagen using the k-means classification method. Consequently, we assume that combining these two techniques in clinics will help to investigate the dilated segment of the aorta with micrometer resolution, which will reduce the possibility of new aneurysm formation due to a segment not excised during the surgery.
dc.description.sponsorshipTürkiye Cumhuriyeti Kalkınma Bakanlığıen_US
dc.identifier.citationTanören, B., Parlatan, U., Parlak, M., Keçoğlu, İ., Burçin Ünlü, M., Öztaş, D. M. ... Uğurlucan, M. (2021). Aortic aneurysm evaluation by scanning acoustic microscopy and Raman spectroscopy. Analytical Methods, 13(39), 4683-4690. https://dx.doi.org/10.1039/d1ay01133b
dc.identifier.doi10.1039/d1ay01133b
dc.identifier.endpage4690
dc.identifier.issn1759-9660
dc.identifier.issue39
dc.identifier.scopusqualityQ2
dc.identifier.startpage4683
dc.identifier.urihttps://dx.doi.org/10.1039/d1ay01133b
dc.identifier.urihttps://hdl.handle.net/20.500.12511/8535
dc.identifier.volume13
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherRoyal Society of Chemistry
dc.relation.ispartofAnalytical Methodsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/embargoedAccess
dc.subjectRaman Spectroscopy
dc.subjectAcoustic Microscopy
dc.subjectAortic Aneurysm
dc.titleAortic aneurysm evaluation by scanning acoustic microscopy and Raman spectroscopy
dc.typeArticle

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