Fructose consumption correlates with triglyceride-glucose index and glycemic status in healthy adults

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dc.authorid0000-0001-7050-9337
dc.contributor.authorKeskin, Eda
dc.contributor.authorYoldaş İlktaç, Havvanur
dc.date.accessioned2022-12-02T10:52:24Z
dc.date.available2022-12-02T10:52:24Z
dc.date.issued2022
dc.departmentİstanbul Medipol Üniversitesi, Sağlık Bilimleri Enstitüsü, Beslenme ve Diyetetik Ana Bilim Dalı
dc.description.abstractBackground and aims: The aim of this study was to evaluate the glycemic parameters, lipid profiles, uric acid levels, and triglyceride-glucose (TyG) index of individuals who consume different amounts of fructose. Additionally, the relationship between the TyG index and the homeostatic model assessment for insulin resistance (HOMA-IR) values was investigated. Methods: This cross-sectional study was conducted on healthy adults aged between 18 and 55 who applied to a university hospital in Istanbul, Turkey. Demographic characteristics and food consumption were recorded using the face-to-face interview method. Participants were divided into two groups according to their fructose consumption (?50 g/day: moderate; >50 g/day: high). The glycemic parameters, lipid profiles, and uric acid levels were measured and TyG index was calculated. Results: Fructose consumption of >50 g/day was reported by 25% of the participants. There was no relationship between lipid profile, uric acid, and fructose consumption. The fasting blood glucose (FBG), fasting insulin, HOMA-IR, and TyG index values in the moderate fructose consumption group were significantly lower than those for the high fructose consumption group (P < 0.05). The TyG index was associated with fructose consumption and HOMA-IR (P < 0.05). High fructose consumers exhibited FBG and HOMA-IR levels 1.18 (95% confidence interval [95% CI] = 1.01–1.37) and 1.42 (95% CI = 1.09–1.84) times higher than those for the moderate fructose consumers (P < 0.05). Conclusions: The results of this study confirmed that high fructose consumption negatively affects glycemic status in healthy adults. Additionally, this study revealed that there is a significant association between daily fructose consumption and TyG index.
dc.identifier.citationKeskin, E. ve Yoldaş İlktaç, H. (2022). Fructose consumption correlates with triglyceride-glucose index and glycemic status in healthy adults. Clinical Nutrition ESPEN, 52, 184-189. https://doi.org/10.1016/j.clnesp.2022.11.008
dc.identifier.doi10.1016/j.clnesp.2022.11.008
dc.identifier.endpage189
dc.identifier.issn2405-4577
dc.identifier.pmid36513452
dc.identifier.scopus2-s2.0-85142181387
dc.identifier.scopusqualityQ2
dc.identifier.startpage184
dc.identifier.urihttps://doi.org/10.1016/j.clnesp.2022.11.008
dc.identifier.urihttps://hdl.handle.net/20.500.12511/10066
dc.identifier.volume52
dc.identifier.wos001081868200001en_US
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorKeskin, Eda
dc.language.isoen
dc.publisherElsevier Ltd
dc.relation.ispartofClinical Nutrition ESPENen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/embargoedAccess
dc.subjectFructose
dc.subjectGlucose
dc.subjectGlycemic Control
dc.subjectInsulin
dc.subjectLipids
dc.subjectTriglyceride-Glucose Index
dc.titleFructose consumption correlates with triglyceride-glucose index and glycemic status in healthy adults
dc.typeArticle

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