Maternal serum galectin-1 and galectin-3 levels in pregnancies complicated with preterm prelabor rupture of membranes

Basit Öğe Kaydı
dc.authorid0000-0002-2257-2355
dc.authorid0000-0003-1257-8742
dc.contributor.authorKaya, Başak
dc.contributor.authorTurhan, Uğur
dc.contributor.authorSezer, Salim
dc.contributor.authorKaya, Serdar
dc.contributor.authorDağ, İsmail
dc.contributor.authorTayyar, Ahmet
dc.date.accessioned2019-12-20T06:18:23Z
dc.date.available2019-12-20T06:18:23Z
dc.date.issued2020
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Kadın Hastalıkları ve Doğum Ana Bilim Dalı
dc.description.abstractObjective: To investigate maternal serum galectin-1 and galectin-3 levels in pregnancies complicated with preterm prelabor rupture of membranes (PPROM) and to compare with pregnancies delivered at term. Materials and methods: In this cross-sectional study, 40 women with singleton pregnancies complicated with PPROM between 24 and 34 weeks of gestation were compared with gestational age-matched 40 pregnant women with no obstetrics complications, who delivered at term. The maternal serum galectin-1 and galectin-3 levels were measured. Results: Patients complicated with PPROM had significantly higher levels of galectin-1 (p = .001) and galectin-3 (p = .003) than the control group. Maternal serum galectin-3 levels were found significantly negatively correlated with the gestational age at delivery and birth weight. Conclusion: Maternal serum galectin-1 and galectin-3 levels were significantly higher in pregnancies complicated with PPROM. Galectin-1 and galectin-3, with their regulatory effects in key biological processes, may be both an initiating factor in the pathophysiology of PPROM, a marker in the prediction, and a target of preventing strategies of PPROM.
dc.identifier.citationKaya, B., Turhan U., Sezer, S., Kaya S., Dağ, İ. ve Tayyar, A. (2020). Maternal serum galectin-1 and galectin-3 levels in pregnancies complicated withpreterm prelabor rupture of membranes. Journal of Maternal-Fetal and Neonatal Medicine, 33(5), 861-868. https://dx.doi.org/10.1080/14767058.2019.1637409
dc.identifier.doi10.1080/14767058.2019.1637409
dc.identifier.endpage868
dc.identifier.issn1476-7058
dc.identifier.issn1476-4954
dc.identifier.issue5
dc.identifier.scopusqualityQ2
dc.identifier.startpage861
dc.identifier.urihttp://dx.doi.org/10.1080/14767058.2019.1637409
dc.identifier.urihttps://hdl.handle.net/20.500.12511/4570
dc.identifier.volume33
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherTaylor and Francis Ltd
dc.relation.ispartofJournal of Maternal-Fetal and Neonatal Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/embargoedAccess
dc.subjectGalectin-1
dc.subjectGalectin-3
dc.subjectLectins
dc.subjectPreterm Birth
dc.subjectPreterm Prelabor Rupture of Membranes
dc.titleMaternal serum galectin-1 and galectin-3 levels in pregnancies complicated with preterm prelabor rupture of membranes
dc.typeArticle

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim Yok
İsim:
Kaya, Basak--2020.pdf
Boyut:
1.21 MB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin / Full Text
İndir

Koleksiyon

Makale Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu