Polycystic ovary syndrome: A disorder of reproductive age, its pathogenesis, and a discussion on the emerging role of herbal remedies

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dc.contributor.authorZeng, Ling-Hui
dc.contributor.authorRana, Saba
dc.contributor.authorHussain, Liaqat
dc.contributor.authorAsif, Muhammad
dc.contributor.authorMehmood, Malik Hassan
dc.contributor.authorImran, Imran
dc.contributor.authorYounas, Anam
dc.contributor.authorMahdy, Amina
dc.contributor.authorAl-Joufi, Fakhria A.
dc.contributor.authorAbed, Shaymaa Najm
dc.date.accessioned2022-08-11T13:42:55Z
dc.date.available2022-08-11T13:42:55Z
dc.date.issued2022
dc.departmentİstanbul Medipol Üniversitesi, Uluslararası Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Tıbbi Farmakoloji Ana Bilim Dalı
dc.description.abstractPolycystic ovary syndrome (PCOS) is a very common, complex, and heterogeneous endocrine disorder of women that involves a combination of environmental and genetic factors. PCOS affects women of growing age particularly at the early to late reproductive stage (15-35 years). Currently, PCOS affects 1 in every 10 women worldwide. It is characterized majorly by a raised level of androgens such as testosterone and a large number of ovarian cysts (more than 10) that cause anovulation, infertility, and irregular menstrual cycle. PCOS is also related to other endocrine and metabolic abnormalities, such as obesity, hirsutism, acne, diabetes, insulin resistance, and glucose impairment. PCOS can be treated with allopathic, ayurvedic, and natural or herbal medications along with lifestyle modifications. Herbal medicines remained in demand for numerous reasons such as high cost and side effects associated with the use of allopathic medicine and our traditional norms, which have helped humans to use more herbal products for their health benefits. Estrogenic and nonestrogenic phytochemicals present in various plant species such as Glycyrrhiza glabra L. [Fabaceae], Aloe vera (L.) Burm. f. [Asphodelaceae], Silybum marianum (L.). Gaertn. [Asteraceae], Serenoa repens (W.Bartram) Small [Arecaceae], Actaea racemosa L. [Ranunculaceae], and Angelica sinensis (Oliv.) Diels [Apiaceae] are effective and harmless. Herbal medicines are found to be cost-effective, efficacious, and a highly esteemed source of management/treatment for PCOS than allopathic medicines. In this literature review, diagnosis, signs, and symptoms of PCOS; causes of hormonal imbalance; and risk factors associated with PCOS and their management are discussed briefly, and the focus was to find out the role of herbal remedies in PCOS management.
dc.identifier.citationZeng, L.-H., Rana, S., Hussain, L., Asif, M., Mehmood, M. H., Imran, I. ... Abed, S. N. (2022). Polycystic ovary syndrome: A disorder of reproductive age, its pathogenesis, and a discussion on the emerging role of herbal remedies. Frontiers in Pharmacology, 13. https://doi.org/10.3389/fphar.2022.874914
dc.identifier.doi10.3389/fphar.2022.874914
dc.identifier.issn1663-9812
dc.identifier.pmid35924049
dc.identifier.scopus2-s2.0-85136342721
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://doi.org/10.3389/fphar.2022.874914
dc.identifier.urihttps://hdl.handle.net/20.500.12511/9644
dc.identifier.volume13
dc.identifier.wos000834549700001en_US
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorMahdy, Amina
dc.language.isoen
dc.publisherFrontiers Media SA
dc.relation.ispartofFrontiers in Pharmacologyen_US
dc.relation.publicationcategoryDiğer
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectPCOS
dc.subjectEndocrine Abnormality
dc.subjectMetabolic Disorder
dc.subjectInfertility
dc.subjectReproduction
dc.titlePolycystic ovary syndrome: A disorder of reproductive age, its pathogenesis, and a discussion on the emerging role of herbal remedies
dc.typeReview Article

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