TSH levels in pregnant women with iodine deficiency before spontaneous abortus

Basit Öğe Kaydı
dc.contributor.authorAtmaca, Murat
dc.contributor.authorÖztürk, Mustafa
dc.contributor.authorÖzbay, Mehmet Fatih
dc.contributor.authorErgenç, E.
dc.contributor.authorGönüllü, Ersin
dc.contributor.authorÇokluk, Erdem
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T19:36:43Z
dc.date.available10.07.201910:49:14
dc.date.available2019-07-10T19:36:43Z
dc.date.issued2014
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıkları Ana Bilim Dalı
dc.description.abstractBackground: Iodine deficiency and/or thyroid autoimmunity are the most common causes of hypothyroidism development among pregnant women. In this study, we aimed to investigate the effect of iodine consumption and thyroid autoimmunity on TSH levels and abortus.The study sample consisted of 104 patients, 79 in abortus and 25 in control groups. TSH, free T4, free T3, anti-TPO, anti-Tg, spot urinary iodine concentrations, and thyroid volumes of the cases were measured by ultrasonography.The spot urine concentration was below 100 µg/L in 93% of the cases included in the study. The TSH levels of the abortus group cases were significantly higher than those of the controls (p=0.025). The percentage of subclinical hypothyroid cases were significantly higher among the cases evaluated due to abortus compared to the control group (p< 0.001). Abortus and control groups did not differ statistically with respect to the presence of autoimmune thyroid diseases (p=0.424). Spot urine iodine concentrations of abortus cases with subclinical hypothyroid were significantly lower than those with TSH levels below the defined range (p=0.001). Spot urine iodine concentrations of the cases with subclinical abortus with negative thyroid autoantibodies were also significantly lower than those with TSH levels below the defined range (p=0.017).TSH levels above 1 µIU/mL for the first trimester and 2 µIU/mL for the second trimester may be indicators of iodine nutrition in pregnancy losses.
dc.identifier.citationAtmaca, M., Öztürk, M. A., Özbay, M. F., Ergenç, E., Gönüllü, E. ve Çokluk, E. (2014). TSH levels in pregnant women with iodine deficiency before spontaneous abortus. Acta Endocrinologica, 10(4), 621-628. https://dx.doi.org/10.4183/aeb.2014.621
dc.identifier.doi10.4183/aeb.2014.621
dc.identifier.endpage628
dc.identifier.issn1841-0987
dc.identifier.issue4
dc.identifier.scopusqualityQ3
dc.identifier.startpage621
dc.identifier.urihttps://hdl.handle.net/20.500.12511/1241
dc.identifier.urihttps://dx.doi.org/10.4183/aeb.2014.621
dc.identifier.volume10
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherActa Endocrinologica Foundation
dc.relation.ispartofActa Endocrinologicaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/embargoedAccess
dc.subjectAbortus
dc.subjectHypothyroidism
dc.subjectLodine Deficiency
dc.titleTSH levels in pregnant women with iodine deficiency before spontaneous abortus
dc.typeArticle

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim Yok
İsim:
Ozturk, Mustafa-2014.pdf
Boyut:
237.65 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin / Full Text
İndir

Koleksiyon

Scopus İndeksli Yayınlar Koleksiyonu
Makale Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu