The natural course of serum D-Dimer, C-Reactive protein, and erythrocyte sedimentation rate levels after uneventful primary total joint arthroplasty

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dc.authorid0000-0003-0926-3029
dc.authorid0000-0002-4883-4317
dc.contributor.authorAzboy, İbrahim
dc.contributor.authorÇatal, Bilgehan
dc.contributor.authorBaşarır, Kerem
dc.contributor.authorMutlu, Müren
dc.contributor.authorBilgen, Ömer Faruk
dc.contributor.authorParvizi, Javad
dc.date.accessioned2021-09-06T11:56:18Z
dc.date.available2021-09-06T11:56:18Z
dc.date.issued2021
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Ortopedi ve Travmatoloji Ana Bilim Dalı
dc.description.abstractBackground: This study aimed to assess the baseline levels of D-dimer, C-reactive protein (CRP), and erythrocyte sedimentation rate (ESR) and monitor the natural course of these serum markers after uneventful primary total joint arthroplasty. Methods: This prospective study enrolled 81 patients undergoing primary total knee arthroplasty or total hip arthroplasty. The level of serum D-dimer, CRP, and ESR was measured preoperatively and on postoperative days 1, 3, 5, 15, and 45. Mean peak values, peak times, and distribution were compared between D-Dimer, CRP, and ESR. Results: The mean preoperative serum D-dimer, CRP, and ESR level was 412 +/- 260 (range 200-980) ng/mL, 2.93 +/- 2.1 (range 1-18) mg/L, and 22.88 +/- 17.5 (range 3-102) mm/h, respectively. The highest mean peak for D-dimer, CRP, and ESR was at postoperative day 1, 3, and 5, respectively. Conclusion: D-dimer levels reached peak levels on postoperative day 1 and then declined rapidly to a plateau level by postoperative day 3. A second, albeit small, peak in the level of D-dimer occurred on postoperative day 15. The level of CRP and ESR remained elevated for much longer with CRP returning to baseline on postoperative day 45 and the level of ESR had not returned back to normal on postoperative day 45.
dc.identifier.citationAzboy, İ., Çatal, B., Başarır, K., Mutlu, M., Bilgen, Ö. F. ve Parvizi, J. (2021). The natural course of serum D-Dimer, C-Reactive protein, and erythrocyte sedimentation rate levels after uneventful primary total joint arthroplasty. The Journal of Arthroplasty, 36(9), 3118-3122. https://dx.doi.org/10.1016/j.arth.2021.04.031
dc.identifier.doi10.1016/j.arth.2021.04.031
dc.identifier.endpage3122
dc.identifier.issn0883-5403
dc.identifier.issn1532-8406
dc.identifier.issue9
dc.identifier.scopusqualityQ1
dc.identifier.startpage3118
dc.identifier.urihttps://dx.doi.org/10.1016/j.arth.2021.04.031
dc.identifier.urihttps://hdl.handle.net/20.500.12511/8010
dc.identifier.volume36
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherChurchill Livingstone Inc Medical Publishers
dc.relation.ispartofThe Journal of Arthroplastyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/embargoedAccess
dc.subjectTotal Joint Arthroplasty
dc.subjectD-Dimer
dc.subjectErythrocyte Sedimentation Rate
dc.subjectC - Reactive Protein
dc.subjectNatural Course
dc.titleThe natural course of serum D-Dimer, C-Reactive protein, and erythrocyte sedimentation rate levels after uneventful primary total joint arthroplasty
dc.typeArticle

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