Radiation recall dermatitis with dabrafenib and trametinib: A case report

dc.authorid0000-0003-0338-8111
dc.contributor.authorYılmaz, Mesut
dc.contributor.authorÇelik, Uğur
dc.contributor.authorHasçiçek, Seyhan
dc.date.accessioned2020-06-10T07:28:48Z
dc.date.available2020-06-10T07:28:48Z
dc.date.issued2020
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Deri ve Zührevi Hastalıklar Ana Bilim Dalı
dc.description.abstractBACKGROUND Radiation recall dermatitis has been defined as the “recalling” by skin of previous radiation exposure in response to the administration of certain response-inducing drugs. Although the phenomenon is relatively well known in the medical world, an exact cause has not been documented. CASE SUMMARY Here, we report the rare occurrence of radiation recall dermatitis after palliative radiotherapy for bone metastases in a metastatic melanoma patient treated with a combination of dabrafenib and trametinib. CONCLUSION We present a case of radiation recall dermatitis after completion of palliative radiotherapy while being treated with a combination of dabrafenib and trametinib. This is a very rare toxic event, and there is insufficient data to describe prevention strategies. Increased awareness and reporting of cases will help to better explain the association between targeted therapy and the radiation recall phenomenon.
dc.identifier.citationYılmaz, M., Çelik, U. ve Hasçiçek, S. (2020). Radiation recall dermatitis with dabrafenib and trametinib: A case report. World Journal of Clinical Cases, 8(3), 522-526. https://dx.doi.org/10.12998/wjcc.v8.i3.522
dc.identifier.doi10.12998/wjcc.v8.i3.522
dc.identifier.endpage526
dc.identifier.issn2307-8960
dc.identifier.issue3
dc.identifier.scopusqualityQ3
dc.identifier.startpage522
dc.identifier.urihttps://dx.doi.org/10.12998/wjcc.v8.i3.522
dc.identifier.urihttps://hdl.handle.net/20.500.12511/5275
dc.identifier.volume8
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherBaishideng Publishing Group
dc.relation.ispartofWorld Journal of Clinical Casesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsAttribution-NonCommercial 4.0 International*
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttps://creativecommons.org/licenses/by-nc/4.0/*
dc.subjectRadiation Recall Dermatitis
dc.subjectMelanoma
dc.subjectRadiotherapy
dc.subjectDabrafenib
dc.subjectTrametinib
dc.subjectCase Report
dc.titleRadiation recall dermatitis with dabrafenib and trametinib: A case report
dc.typeArticle

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