Left atrial expansion index is an independent predictor of diastolic dysfunction in patients with preserved left ventricular systolic function: A three dimensional echocardiography study

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dc.contributor.authorHatipoğlu, Suzan
dc.contributor.authorÖzdemir, Nihal
dc.contributor.authorBabür Güler, Gamze
dc.contributor.authorOmaygenç, Mehmet Onur
dc.contributor.authorBakal, Ruken Bengi
dc.contributor.authorKahveci, Gökhan
dc.contributor.authorUnkun, Tuba
dc.contributor.authorŞahin, Gülsüm
dc.contributor.authorKaymaz, Cihangir
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T19:56:34Z
dc.date.available10.07.201910:49:13
dc.date.available2019-07-10T19:56:34Z
dc.date.issued2014
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Kardiyoloji Ana Bilim Dalı
dc.descriptionWOS: 000342453600015
dc.descriptionPubMed ID: 24958524
dc.description.abstractIn the absence of mitral valve disease left atrial (LA) volume is a marker of diastolic dysfunction and its severity. This study investigated the relationship between left ventricular (LV) end diastolic pressure (LVEDP) and LA volumes and phasic atrial functions detected by real-time full volume three-dimensional echocardiography (RT3DE), in a patient population with preserved LV systolic function. Seventy-two (39 female and 33 male; mean age 56.1 +/- A 9.0 years) stable patients with normal LV ejection fraction (EF) undergoing cardiac catheterization were studied. All patients underwent comprehensive echocardiographic examination just before catheterization and LVEDP was obtained. In addition to conventional echocardiographic measurements and Doppler indices; by using RT3DE LA maximum, minimum and pre-a-wave volumes were measured; LA total, passive and active emptying volumes and fractions were calculated. LV systolic function was assessed by EF and global longitudinal strain by speckle tracking. RT3DE minimum LA volume index, RT3DE active LAEF and LA expansion index (EI) were statistically significant univariate predictors of LVEDP a parts per thousand yen 16 mmHg. When age and hypertension adjusted multivariate analysis was performed EI [beta = -1.741, p = 0.015; OR 0.175; 95 % CI (0.043-0.717)] was an independent predictor of elevated LVEDP. RT3DE evaluation of LA function during entire cardiac cycle has incremental value for the diagnosis of diastolic dysfunction in patients with preserved EF. We suggest that RT3DE evaluation of LA may find clinical application in this field.
dc.identifier.citationHatipoğlu, S., Özdemir, N., Babür Güler, G., Omaygenç, M. O., Bakal, R. B., Kahveci, G. ... Kaymaz, C. (2014). Left atrial expansion index is an independent predictor of diastolic dysfunction in patients with preserved left ventricular systolic function: A three dimensional echocardiography study. The International Journal of Cardiovascular Imaging, 30(7), 1315-1323. https://dx.doi.org/10.1007/s10554-014-0476-y
dc.identifier.doi10.1007/s10554-014-0476-y
dc.identifier.endpage1323
dc.identifier.issn1569-5794
dc.identifier.issn1573-0743
dc.identifier.issue7
dc.identifier.scopusqualityQ1
dc.identifier.startpage1315
dc.identifier.urihttps://dx.doi.org/10.1007/s10554-014-0476-y
dc.identifier.urihttps://hdl.handle.net/20.500.12511/2749
dc.identifier.volume30
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherSpringer
dc.relation.ispartofThe International Journal of Cardiovascular Imagingen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectLeft Atrial Volume
dc.subjectDiastolic Dysfunction
dc.subjectLeft Ventricular end Diastolic Pressure
dc.subjectReal-Time Three-Dimensional Echocardiography
dc.titleLeft atrial expansion index is an independent predictor of diastolic dysfunction in patients with preserved left ventricular systolic function: A three dimensional echocardiography study
dc.typeArticle

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