Association between 25-hydroxy vitamin D3 levels and thyroiditis staged by using ultrasonography

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dc.authorid0000-0002-6315-1848
dc.authorid0000-0001-8532-4917
dc.contributor.authorÇolakoğulları, Mukaddes
dc.contributor.authorKarataş, Lokman
dc.contributor.authorÖrmeci, Tuğrul
dc.date.accessioned2024-08-27T11:06:30Z
dc.date.available2024-08-27T11:06:30Z
dc.date.issued2024
dc.departmentİstanbul Medipol Üniversitesi, Sağlık Bilimleri Enstitüsü
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Radyoloji Ana Bilim Dalı
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Tıbbi Biyokimya Ana Bilim Dalı
dc.description.abstractVitamin D deficiency has been linked to a higher prevalence of thyroid gland impairment. The association between 25-hydroxy Vitamin D3 concentrations and sonographic changes of thyroiditis was investigated. A total of 55 patients were divided into 3 groups according to the thyroid ultrasonography (US) findings: Group 1: control cases (n=17); Group 2: intermediate (early) cases (n=14); and Group 3: active and late-stage thyroiditis cases (n=24). Serum 25-hydroxy Vitamin D concentrations, thyroid hormones (free T3, free T4, TSH) and antibody levels (TPO Ab, Tg Ab) were assessed in different stages of thyroiditis. The Vitamin D concentrations of Group 1 (28.54 ± 20.43 ng/dL) were significantly higher than those of Group 2 (14.48 ± 5.87 ng/mL) and Group 3 (14.3 ± 9.2 ng/dL) (p=0.025 and p=0.004, respectively). Tg Ab and TPO Ab significantly increased in Group 3 compared to Groups 1 and 2 (p<0.001, p<0.001, respectively). 25-hydroxy Vitamin D3 deficiency was associated with thyroid gland morphological changes detected by ultrasonography.
dc.identifier.citationÇolakoğulları, M., Karataş, L. ve Örmeci, T. (2024). Association between 25-hydroxy vitamin D3 levels and thyroiditis staged by using ultrasonography. Acta Pharmaceutica Sciencia, 62(3), 533-544. http://dx.doi.org/10.23893/1307-2080.APS6233
dc.identifier.doi10.23893/1307-2080.APS6233
dc.identifier.endpage544
dc.identifier.issn1307-2080
dc.identifier.issue3
dc.identifier.scopus2-s2.0-85199333063
dc.identifier.scopusqualityQ3
dc.identifier.startpage533
dc.identifier.urihttp://dx.doi.org/10.23893/1307-2080.APS6233
dc.identifier.urihttps://hdl.handle.net/20.500.12511/12780
dc.identifier.volume62
dc.indekslendigikaynakScopus
dc.institutionauthorÇolakoğulları, Mukaddes
dc.institutionauthorKarataş, Lokman
dc.institutionauthorÖrmeci, Tuğrul
dc.language.isoen
dc.relation.ispartofActa Pharmaceutica Scienciaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subject25-OH Vitamin D3
dc.subjectAnti-Tg
dc.subjectAnti-TPO
dc.subjectAutoimmune Thyroiditis
dc.subjectSonography
dc.titleAssociation between 25-hydroxy vitamin D3 levels and thyroiditis staged by using ultrasonography
dc.typeArticle

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