Sedation with ketamine-propofol in patients undergoing transcatheter aortic valve implantation: a comparative retrospective study on general anesthesia

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dc.authorid0000-0001-9531-4317
dc.contributor.authorYılmaz, Nurdan
dc.contributor.authorGül, Yaşar Gökhan
dc.contributor.authorUğurlucan, Murat
dc.date.accessioned2024-09-23T12:25:23Z
dc.date.available2024-09-23T12:25:23Z
dc.date.issued2024
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Anesteziyoloji ve Reanimasyon Ana Bilim Dalı
dc.description.abstractBackground: Transcatheter aortic valve implantation (TAVI) is used for patients with severe aortic stenosis who are at high risk for surgery. Since these patients are elderly and have comorbidities, their management is of great importance. Objectives: This retrospective study compares two anesthesia techniques during TAVI: sedation (ket-amine and propofol) and general anesthesia. Methods: Patients with severe aortic stenosis undergoing TAVI during 2021 in our hospital were retrospectively screened. Demographic data, comorbidities, anesthesia management, complications, and mortality of the patients were obtained from the records. Results: There were 137 patients treated with TAVI; 74 (54%) patients had sedation and 63 (46%) had general anesthesia. When the anesthesia management was evaluated, no significant difference in mortality was observed between the patients who received general anesthesia and sedation. After univariate and multivariate logistic regression analyses were performed to investigate factors having an impact on mortality, anemia (only in univariate analysis) in the whole study population was a statistically significant risk factor for mortality in patients undergoing TAVI (p<0.014). Conclusion: There was no significant difference in mortality in terms of anesthesia management. Anemia was a risk factor for mortality (only in univariate analysis) in the whole study population. We concluded that conscious sedation with ketamine and propofol is effective and safe for TAVI procedures compared to general anesthesia.
dc.identifier.citationYılmaz, N., Gül, Y. G. ve Uğurlucan, M. (2024). Sedation with ketamine-propofol in patients undergoing transcatheter aortic valve implantation: a comparative retrospective study on general anesthesia. Current Vascular Pharmacology, 22(4), 266-272. http://dx.doi.org/10.2174/0115701611274790231221044147
dc.identifier.doi10.2174/0115701611274790231221044147
dc.identifier.endpage272
dc.identifier.issn1570-1611
dc.identifier.issn1875-6212
dc.identifier.issue4
dc.identifier.pmid38284695
dc.identifier.scopus2-s2.0-85200571541
dc.identifier.scopusqualityQ1
dc.identifier.startpage266
dc.identifier.urihttp://dx.doi.org/10.2174/0115701611274790231221044147
dc.identifier.urihttps://hdl.handle.net/20.500.12511/12827
dc.identifier.volume22
dc.identifier.wos001158651200001en_US
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorYılmaz, Nurdan
dc.institutionauthorGül, Yaşar Gökhan
dc.language.isoen
dc.relation.ispartofCurrent Vascular Pharmacologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectGeneral Anesthesia
dc.subjectKetamine
dc.subjectPropofol
dc.subjectSedation
dc.subjectSevere Aortic Ste-Nosis
dc.subjectTranscatheter Aortic Valve Implantation (TAVI)
dc.titleSedation with ketamine-propofol in patients undergoing transcatheter aortic valve implantation: a comparative retrospective study on general anesthesia
dc.typeArticle

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