Association of severity of helicobacter pylori infection with peripheral blood neutrophil to lymphocyte ratio and mean platelet volume

dc.contributor.authorGüçlü, Mustafa
dc.contributor.authorAgan, A. Faruq
dc.date.accessioned2020-07-20T13:29:40Z
dc.date.available2020-07-20T13:29:40Z
dc.date.issued2017
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıkları Ana Bilim Dalı
dc.description.abstractAim: To determine the correlation of Helicobacter pylori infection with peripheral blood neutrophil/lymphocyteratio (NLR) and mean platelet volume (MPV).Materials and methods: The NLR, MPV, platelets, leukocytes, neutrophils, and lymphocytes were calculatedand the differences between groups were investigated.Results: A total of 199 patients were included in the study. Neutrophil/lymphocyte ratio was statistically lower inH. pylori-positive patients than in H. pylori-negative patients (1.94 ± 0.79 vs 2.67 ± 2.35 respectively, p = 0.04).There was no significant difference between H. pylori-negative patients and H. pylori-positive patients of severeintensity in terms of MPV. However, peripheral blood lymphocytes and platelets were statistically significantlyhigher in H. pylori-positive patients of severe intensity (lymphocytes 2150 ± 826 vs 2954 ± 2436 respectively,p = 0.000 and platelets 258247 ± 69494 vs 265611 ± 113397 respectively, p = 0.02) compared with H. pylorinegative patients.Conclusion: A moderate increase in the intensity of H. pylori does not lead to a significant change in MPV asmeasured by hemogram; however, it gives rise to a statistically significant fall in NLR. Presence of severe H.pylori-positive intensity leads to a statistically significant increase in peripheral blood lymphocytes and plateletscompared with H. pylori-negative patients.
dc.identifier.citationGüçlü, M. ve Agan, A. F. (2017). Association of severity of helicobacter pylori infection with peripheral blood neutrophil to lymphocyte ratio and mean platelet volume. Euroasian Journal of Hepato-Gastroenterology, 7(1), 11-16. https://dx.doi.org/10.5005/jp-journals-10018-1204
dc.identifier.doi10.5005/jp-journals-10018-1204
dc.identifier.endpage16
dc.identifier.issn2231-5047
dc.identifier.issn2231-5128
dc.identifier.issue1
dc.identifier.startpage11
dc.identifier.urihttps://dx.doi.org/10.5005/jp-journals-10018-1204
dc.identifier.urihttps://hdl.handle.net/20.500.12511/5579
dc.identifier.volume7
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherJaypee
dc.relation.ispartofEuroasian Journal of Hepato-Gastroenterologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsAttribution 3.0 Unported*
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttps://creativecommons.org/licenses/by/3.0/*
dc.subjectHelicobacter Pylori
dc.subjectMean Platelet Volume
dc.subjectNeutrophil to Lymphocyte Ratio
dc.titleAssociation of severity of helicobacter pylori infection with peripheral blood neutrophil to lymphocyte ratio and mean platelet volume
dc.typeArticle

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