Efficacy of a casein phosphopeptide amorphous calcium phosphate (CPP-ACP) paste in preventing white spot lesions in patients with fixed orthodontic appliances: A prospective clinical trial

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dc.contributor.authorEsenlik, Elçin
dc.contributor.authorÜzer Çelik, Esra
dc.contributor.authorBolat, Ertuğrul
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T19:52:39Z
dc.date.available10.07.201910:49:13
dc.date.available2019-07-10T19:52:39Z
dc.date.issued2016
dc.departmentİstanbul Medipol Üniversitesi, Diş Hekimliği Fakültesi, Ortodonti Ana Bilim Dalı
dc.descriptionWOS: 000392570500005
dc.descriptionPubMed ID: 28045314
dc.description.abstractAim: The aim of this prospective study was to test the efficacy of casein phosphopeptide amorphous calcium phosphate (CPP-ACP) paste applied in-office to prevent white spot lesions (WSL) in patients undergoing fixed orthodontic treatment. Materials and methods: Study design: this study was designed as a randomised controlled clinical trial. Fifty-seven patients undergoing nonextraction fixed orthodontic treatment were enrolled and divided randomly into two groups (control n = 28, experimental n = 29). The pretreatment plaque, gingival and bleeding indices, and oral hygiene habits were recorded. One group received CPP-ACP paste (GC Tooth Mousse) at each monthly orthodontic follow-up examination; the control group received routine orthodontic treatment. The mean patient age was 16.9 years in the experimental group and 17.1 years in the control group. The periodontal indices, decayed, missing, and filled teeth (DMFT), decayed, missing, and filled surfaces (DMFS), and the WSL prevalence pre- and post-treatment were measured and compared between the groups. Statistics: differences between groups in normally distributed data between groups were assessed by the paired-t test, and the Wilcoxon Signed Rank test was used to compare variables that were not normally distributed. Results: There was a lower incidence of WSL in the experimental group compared to the control group. Most of the WSL occurred at the maxillary incisors, mandibular canines and premolars. Conclusion: The in-office application of CPP-ACP paste did not prevent WSL development completely; however, it did significantly decrease the number of WSL compared to the control patients.
dc.identifier.citationEsenlik, E., Üzer Çelik, E. ve Bolat, E. (2016). Efficacy of a casein phosphopeptide amorphous calcium phosphate (CPP-ACP) paste in preventing white spot lesions in patients with fixed orthodontic appliances: A prospective clinical trial. European Journal Of Paediatric Dentistry, 17(4), 274-280.
dc.identifier.endpage280
dc.identifier.issn1591-996X
dc.identifier.issn2035-648X
dc.identifier.issue4
dc.identifier.scopusqualityQ2
dc.identifier.startpage274
dc.identifier.urihttps://hdl.handle.net/20.500.12511/2439
dc.identifier.volume17
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherAriesdue SRL
dc.relation.ispartofEuropean Journal Of Paediatric Dentistryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectCPP-ACP Paste
dc.subjectFixed Orthodontic
dc.subjectTreatment
dc.subjectWhite Spot Lesions
dc.titleEfficacy of a casein phosphopeptide amorphous calcium phosphate (CPP-ACP) paste in preventing white spot lesions in patients with fixed orthodontic appliances: A prospective clinical trial
dc.typeArticle

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