Neutrophil/lymphocyte ratio can predict postoperative mortality in patients with chronic thromboembolic pulmonary hypertension

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dc.contributor.authorYanartaş, Mehmet
dc.contributor.authorKalkan, Mehmet Emin
dc.contributor.authorArslan, Akın
dc.contributor.authorTaş, Serpil Gezer
dc.contributor.authorKöksal, Cengiz
dc.contributor.authorBekiroğlu, Nural
dc.contributor.authorYıldızeli, Bedrettin
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T19:36:18Z
dc.date.available10.07.201910:49:14
dc.date.available2019-07-10T19:36:18Z
dc.date.issued2015
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Kalp ve Damar Cerrahisi Ana Bilim Dalı
dc.description.abstractObjective: The aim of our study was to investigate clinical importance of neutrophil/ lymphocyte ratio in patients with Chronic thromboembolic pulmonary hypertension. Methods: 125 consecutive patients with a diagnosis of Chronic thromboembolic pulmonary hypertension were operated pulmonary thromboendarterectomy in our center between February 2011 and August 2013. 106 patients included into the study due to limitations. The patients were classified into two groups as patients discharged alive (Group 1) and those dying in the hospital (Group 2). Baseline neutrophil/lymphocyte ratio level was measured by dividing neutrophil count to lymphocyte count. Results: 84 patients (79%) were in Group 1, 22 patients (21%) were in Group 2. Patients with higher neutrophil/lymphocyte ratio in admission have a significantly higher mortality rate and postoperative pulmonary vascular resistance was found statistically significant variable to predict the mortality. Receiver operator characteristic (ROC) analysis revealed that using a cut-off point of 2.54, admission neutrophil/lymphocyte ratio predicts mortality. Also, correlation analysis showed a significant correlation between preopera-tive pulmonary vascular resistance and neutrophil/lymphocyte ratio. Conclusion: The neutrophil/lymphocyte ratio level may be a useful and noninvasive biomarker for operative risk stratification for mortality after pulmonary thromboendarterectomy.
dc.identifier.citationYanartaş, M., Kalkan, M. E., Arslan, A., Taş, S. G., Köksal, C., Bekiroğlu, N. ... Yıldızeli, B. (2015). Neutrophil/lymphocyte ratio can predict postoperative mortality in patients with chronic thromboembolic pulmonary hypertension. Annals of Thoracic and Cardiovascular Surgery, 21(3), 229-235. https://dx.doi.org/10.5761/atcs.oa.14-00190
dc.identifier.doi10.5761/atcs.oa.14-00190
dc.identifier.endpage235
dc.identifier.issn1341-1098
dc.identifier.issue3
dc.identifier.scopusqualityQ3
dc.identifier.startpage229
dc.identifier.urihttps://hdl.handle.net/20.500.12511/1124
dc.identifier.urihttps://dx.doi.org/10.5761/atcs.oa.14-00190
dc.identifier.volume21
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherJapanese Association for Coronary Artery Surgery
dc.relation.ispartofAnnals of Thoracic and Cardiovascular Surgeryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectChronic Thromboembolic Pulmonary Hypertension
dc.subjectInfammation
dc.subjectNeutrophil/lymphocyte Ratio
dc.subjectPulmonary Thromboendarterec-Tomy
dc.subjectPulmonary Vascular Resistance
dc.titleNeutrophil/lymphocyte ratio can predict postoperative mortality in patients with chronic thromboembolic pulmonary hypertension
dc.typeArticle

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